Evidence map›Paper›PMID 34357962›Full record

ReviewToxins2021

Bacterial Type I Toxins: Folding and Membrane Interactions.

Sylvie Nonin-Lecomte, Laurence Fermon, Brice Felden, Marie-Laure Pinel-Marie

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Toxins · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. ComI inhibits transformation inJournal of bacteriology · 2024
    Article
  12. Article
  13. Article
  14. Mechanism of action ofFrontiers in microbiology · 2023
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. TheToxins · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sylvie Nonin-LecomteCiTCoM, CNRS, UMR 8038, Université de Paris, 93526 Paris, France.ORCID 0000-0001-5155-8088
Laurence FermonBRM (Bacterial Regulatory RNAs and Medicine), Inserm, UMR_S 1230, Université de Rennes 1, 35000 Rennes, France.
Brice FeldenBRM (Bacterial Regulatory RNAs and Medicine), Inserm, UMR_S 1230, Université de Rennes 1, 35000 Rennes, France.ORCID 0000-0003-2803-0626
Marie-Laure Pinel-MarieBRM (Bacterial Regulatory RNAs and Medicine), Inserm, UMR_S 1230, Université de Rennes 1, 35000 Rennes, France.ORCID 0000-0001-5128-0741
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial type I toxin-antitoxin systems are two-component genetic modules that encode a stable toxic protein whose ectopic overexpression can lead to growth arrest or cell death, and an unstable RNA antitoxin that inhibits toxin translation during growth. These systems are widely spread among bacterial species. Type I antitoxins are

Indexed as

AntitoxinsBacteriaBacterial ProteinsBacterial ToxinsGene Expression Regulation, BacterialGram-Positive BacteriaRibonucleasesRNA, BacterialRNA, MessengerStaphylococcal InfectionsStaphylococcus aureusToxin-Antitoxin SystemsAntitoxinsBacterial ProteinsBacterial ToxinsRibonucleasesRNA, BacterialRNA, Messengerfoldingmechanisms of actionmembrane depolarizationmembrane permeabilizationnucleoid condensationpore formationstructuretoxin-antitoxin systemstype I toxins

Identifiers

PMID34357962
PMCPMC8309996
OpenAlexW3186472822

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.