Evidence map›Paper›PMID 34357952›Full record

ArticleToxins2021

Human Peptides α-Defensin-1 and -5 Inhibit Pertussis Toxin.

Carolin Kling, Arto T Pulliainen, Holger Barth, Katharina Ernst

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Effects of Bile on PathogenicBiomolecules · 2025
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Carolin KlingInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Arto T PulliainenInstitute of Biomedicine, Research Unit for Infection and Immunity, University of Turku, FI-20520 Turku, Finland.
Holger BarthInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Katharina ErnstInstitute of Pharmacology and Toxicology, Ulm University Medical Center, 89081 Ulm, Germany.
Universität Ulm · DEUniversity of Turku · FI

Funding

Deutsche Forschungsgemeinschaft 316249678 (A07, funding to K.E.; C02, funding to H.B.)European Social Fund Margarete von Wrangell Habilitation programMinisterium für Wissenschaft, Forschung und Kunst Baden-Württemberg Margarete von Wrangell Habilitation program
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

alpha-DefensinsAnimalsAnti-Infective AgentsAntimicrobial PeptidesBordetella pertussisChildHumansPertussis ToxinVirulence Factors, BordetellaWhooping Coughalpha-DefensinsAnti-Infective AgentsAntimicrobial Peptideshuman neutrophil peptide 1Pertussis ToxinVirulence Factors, BordetellaADP-ribosylating toxinantimicrobial peptidebacterial AB-type toxindefensinshuman peptidepertussis toxintoxin inhibitor

Identifiers

PMID34357952
PMCPMC8310310
OpenAlexW3178715282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.