ArticleTransboundary and emerging diseases2022
Repetitive saliva-based mass screening as a tool for controlling SARS-CoV-2 transmission in nursing homes.
Article in Transboundary and emerging diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- A one-step low-cost molecular test for SARS-CoV-2 detection suitable for community testing using minimally processed saliva.Biology methods & protocols · 2024Article
- Developing a Video Game as an Awareness and Research Tool Based on SARS-CoV-2 Epidemiological Dynamics and Motivational Perspectives.Transboundary and emerging diseases · 2023Article
- Comparison of SARS-CoV-2 Detection from Saliva Sampling and Oropharyngeal Swab.Microbiology spectrum · 2022Article
- Repetitive saliva-based mass screening as a tool for controlling SARS-CoV-2 transmission in nursing homes.Transboundary and emerging diseases · 2022Article
- Mass screening is a key component to fight against SARS-CoV-2 and return to normalcy.Medical review (2021) · 2022Review
- Decision-based interactive model to determine re-opening conditions of a large university campus in Belgium during the first COVID-19 wave.Archives of public health = Archives belges de sante publique · 2022Article
- Factors influencing the adoption and participation rate of nursing homes staff in a saliva testing screening programme for COVID-19.PloS one · 2022Article
- A 2-month field cohort study of SARS-CoV-2 in saliva of BNT162b2 vaccinated nursing home workers.Communications medicine · 2022Article
- Acceptability of Community Saliva Testing in Controlling the COVID-19 Pandemic: Lessons Learned from Two Case Studies in Nursing Homes and Schools.Patient preference and adherence · 2022Article
- Regular monitoring of SARS-CoV-2 carriage and antibody levels against the virus helped maintain social interactions for Alzheimer's disease residents in a Belgian nursing home during the pandemic.Journal of Alzheimer's disease reportsArticle
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Authors and funding
18 authors at 3 institutions in 1 country.
Funding
Abstract
Nursing home (NH) residents and staff have been severely affected by the COVID-19 pandemic. The aim of this study was to examine the use of weekly saliva RT-qPCR testing for SARS-CoV-2 detection among NH workers as a strategy to control disease transmission within NHs in Belgium. From 16 November to 27 December 2020, a voluntary and anonymous weekly screening was implemented in a cohort of 50,000 workers across 572 NHs in the Walloon region of Belgium to detect asymptomatic cases of SARS-CoV-2 via saliva RT-qPCR testing and using the Diagenode saliva sample collection device. Positive workers were isolated to avoid subsequent infections in residents and other staff. RT-qPCR testing was based on pooled saliva sampling techniques from three workers, followed by individual testing of each positive or inconclusive pool. The majority of NHs (85%) and 55% of their workers participated. Pooling did not affect sensitivity as it only induced a very decrease in sensitivity estimated as 0.33%. Significant decreases in the prevalence (34.4-13.4%) and incidence of NHs with either single (13.8-2%) or multiple positive workers (3.7-0%) were observed over time. In addition, deaths among NH residents and NH worker absences decreased significantly over time. Weekly saliva RT-qPCR testing for SARS-CoV-2 demonstrated large-scale feasibility and efficacy in disrupting the chain of transmission. Implementation of this testing strategy in NHs could also be extended to other settings with the aim to control viral transmission for maintaining essential activities.
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Registered trials
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