ArticleJournal of general internal medicine2022
The Fragility Index for Assessing the Robustness of the Statistically Significant Results of Experimental Clinical Studies.
Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Exploring the fragility of meta-analyses in ophthalmology: a systematic review.Eye (London, England) · 2024Pooled it
- The Continuous Fragility Index of Statistically Significant Findings in Randomized Controlled Trials That Compare Interventions for Anterior Shoulder Instability.The American journal of sports medicine · 2024Pooled it
- The Statistical Fragility of Operative vs Nonoperative Management for Achilles Tendon Rupture: A Systematic Review of Comparative Studies.Foot & ankle international · 2022Pooled it
- β-Blockers after myocardial infarction with preserved or mildly reduced left ventricular ejection fraction: Fragility of contemporary evidence.American heart journal plus : cardiology research and practice · 2026Article
- Direct oral anticoagulants in cancer-associated venous thromboembolism: trial robustness and clinical trade-offs.Research and practice in thrombosis and haemostasis · 2026Article
- Robustness and fragility of evidence supporting systemic thrombolysis in acute pulmonary embolism.Journal of thrombosis and thrombolysis · 2026Article
- Concerns regarding the prognostic validity and analytical coherence of total protein-to-albumin ratio in diabetic kidney disease.International urology and nephrology · 2026Article
- Reconsidering the link between obstructive sleep apnea and intracranial collateral circulation in stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Evaluating the properties of the fragility index of meta-analyses.BMC medical research methodology · 2025Article
- Kinematic vs. mechanical alignment in total knee arthroplasty: A statistical analysis of randomized control trials utilizing dichotomous and continuous fragility metrics.Journal of orthopaedics · 2025Review
- The Role of Double-Zero-Event Studies in Evidence Synthesis: Evaluating Robustness Using the Fragility Index.Journal of evaluation in clinical practice · 2025Article
- Fragility in cardiovascular randomized controlled trials with primary continuous outcomes (2018-2022) from multi-perspectives assessment: a cross-sectional survey.Annals of medicine · 2024Article
- Assessing robustness of results of randomised clinical trials using Fragility Index.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- The Fragility of Statistically Significant Binary Outcomes for Treating Achilles Tendinopathy: A Systematic Review of Randomized Trials.Foot & ankle orthopaedics · 2024Article
- Fragility analysis and systematic review of patellar resurfacing versus non-patellar resurfacing in total knee arthroplasty.Journal of experimental orthopaedics · 2024Article
- Empirical assessment of fragility index based on a large database of clinical studies in the Cochrane Library.Journal of evaluation in clinical practice · 2023Article
- Assessing the robustness of results from clinical trials and meta-analyses with the fragility index.American journal of obstetrics and gynecology · 2023Review
- The Statistical Fragility of Platelet-Rich Plasma as Treatment for Plantar Fasciitis: A Systematic Review and Simulated Fragility Analysis.Foot & ankle orthopaedics · 2022Article
- The Statistical Fragility of Platelet-Rich Plasma as Treatment for Chronic Noninsertional Achilles Tendinopathy: A Systematic Review and Meta-analysis.Foot & ankle orthopaedics · 2022Article
- Tips for Busy Clinicians to Gauge Conclusions from Clinical Trials.Journal of general internal medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.