Evidence map›Paper›PMID 34357567›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2021

Intraoperative end-tidal carbon dioxide and postoperative mortality in major abdominal surgery: a historical cohort study.

Li Dong, Chikashi Takeda, Hajime Yamazaki, Tsukasa Kamitani, Miho Kimachi, Miho Hamada, Shunichi Fukuhara, Toshiyuki Mizota, Yosuke Yamamoto

Registry-linked trialAbstract read
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In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05550181 (Associations of Intraoperative Hypocapnia With Patient Demographics, Ventilation Characteristics and Outcomes--Statistical Analysis Plan for an Individual Patient Data Analysis of PROVHILO and PROBESE), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05550181 completednot on this mapstarted 2022, after this paper: background citation

Associations of Intraoperative Hypocapnia With Patient Demographics, Ventilation Characteristics and Outcomes--Statistical Analysis Plan for an Individual Patient Data Analysis of PROVHILO and PROBESE

TypeobservationalSponsorNMC Specialty HospitalRan2022 to 2023Enrolled2,793ConditionsMechanical Ventilation Complication, Surgery, Pulmonary Complication, Intraoperative ComplicationsArmsintraoperative mechanical ventilation with hypocapnia (etCO2 < 35 mm Hg)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Li DongDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Chikashi TakedaDepartment of Anesthesia, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Kyoto, 606-8507, Japan.
Hajime YamazakiSection of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tsukasa KamitaniDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Miho KimachiDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
Miho HamadaDepartment of Anesthesia, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Kyoto, 606-8507, Japan.
Shunichi FukuharaSection of Clinical Epidemiology, Department of Community Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Toshiyuki MizotaDepartment of Anesthesia, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Kyoto, 606-8507, Japan. mizota@kuhp.kyoto-u.ac.jp.ORCID http://orcid.org/0000-0003-2770-4262
Yosuke YamamotoDepartment of Healthcare Epidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.

Funding

the Japan Society for the Promotion of Science KAKENHI program 20K09242
6 · The paper itself

Abstract

purposeThere is a paucity of data on the effect of intraoperative end-tidal carbon dioxide (EtCO

methodsWe conducted a historical cohort study of patients undergoing major abdominal surgery under general anesthesia at Kyoto University Hospital. We measured the intraoperative EtCO

resultsOf 4,710 patients, 1,374 (29%) had low EtCO

conclusionA mean intraoperative EtCO

Indexed as

Anesthesia, GeneralCarbon DioxideCohort StudiesHumansPostoperative PeriodRetrospective StudiesCarbon DioxideEnd-tidal carbon dioxideIntraoperative hypocapniaMajor abdominal surgeryPostoperative mortality

Identifiers

PMID34357567

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.