Evidence map›Paper›PMID 34357432›Full record

Trial reportInternational orthopaedics2021

Reduced pre-operative skin oxygen saturation predicts revision after open reduction and internal fixation in calcaneal fractures : A reduced pre-operative oxygen saturation as measured by laser-Doppler spectrophotometry in 8 mm depth is associated with revision surgery after open reduction and internal fixation of calcaneal fractures through an extended lateral approach.

Matthias Knobe, Lukas D Iselin, Bryan J M van de Wall, Philipp Lichte, Frank Hildebrand, Frank J P Beeres, Björn-Ch Link, Boyko Gueorguiev, Sven Nebelung, Bergita Ganse and 4 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01264146 (Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01264146 nacompletednot on this map

Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?

TypeinterventionalSponsorRWTH Aachen UniversityRan2011 to 2012Enrolled20ConditionsMicrocirculation, Wound HealingArmsHBOT, Placebo (Sham)
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Predictors for wound healing complications and prolonged hospital stay in patients with isolated calcaneal fractures.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Matthias KnobeDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland. matthias.knobe@luks.ch.ORCID 0000-0002-9166-0965
Lukas D IselinDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
Bryan J M van de WallDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
Philipp LichteDepartment of Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Frank HildebrandDepartment of Trauma and Reconstructive Surgery, University Hospital RWTH Aachen, Aachen, Germany.
Frank J P BeeresDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
Björn-Ch LinkDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
Boyko GueorguievAO Research Institute Davos, Davos, Switzerland.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, University Düsseldorf, Düsseldorf, Germany.
Bergita GanseWerner Siemens Foundation Endowed Chair for Innovative Implant Development, Clinics and Institutes of Surgery, Saarland University, Homburg, Germany.
Filippo MiglioriniDepartment of Orthopaedics, University Hospital RWTH Aachen, Aachen, Germany.
Kajetan KlosGelenkzentrum Rhein-Main, Hochheim am Main, Germany.
Reto BabstDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
Pascal C HaefeliDepartment of Orthopaedic and Trauma Surgery, Lucerne Cantonal Hospital, 6000, Luzern 16, Switzerland.
University of Lucerne · CHRWTH Aachen University · DEAO Foundation · CHHeinrich Heine University Düsseldorf · DESiemens (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess which pre-operative parameters correlate with wound revisions after an extended lateral approach to the calcaneus.

methodsPre-operative laser-Doppler spectrophotometry was applied in patients undergoing open reduction and internal fixation. The number of wound revisions was recorded during pos-toperative follow-up. Spearman rho analysis was used to identify factors associated with wound revision and receiver operator characteristics curves were calculated for the identified factors.

resultsThirty-four patients (29 men, 5 women; 37 calcanei) with a mean patient age of 43 ± 14 years were analyzed. The minimal oxygen saturation value at the five measurement locations as well as the minimal value for flow correlated negatively with wound revisions (p value = 0.025 and 0.038, respectively). The area under the curve for the pre-operative minimal value of oxygen saturation was 0.841 (95%CI 0.64-1.00, p = 0.028), indicating a good accuracy as a test to predict wound revision.

conclusionA pre-operative oxygen saturation of at least 20.5% across five measurement points along the anticipated incision identified all patients not needing a wound revision (negative predictive value 100%). On the other hand, patients with at least one measurement below 20.5% were at risk for wound revision surgery (sensitivity 100%, specificity 48.5%). ClinicalTrials.gov NCT01264146.

Indexed as

CalcaneusFractures, BoneAdultFemaleFracture Fixation, InternalHumansLasersMaleMiddle AgedOxygenReoperationRetrospective StudiesSpectrophotometryOxygenCalcaneal fractureFoot traumaLateral extended approachMicrocirculationORIFPre-operative diagnosticsSpectrophotometry

Identifiers

PMID34357432
OpenAlexW3192756422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.