Evidence map›Paper›PMID 34357348›Full record

ArticleMetabolites2021

Progression of Postprandial Blood Plasma Phospholipids Following Acute Intake of Different Dairy Matrices: A Randomized Crossover Trial.

Rebekka Thøgersen, Ida Emilie I Lindahl, Bekzod Khakimov, Louise Kjølbæk, Klaus Juhl Jensen, Arne Astrup, Marianne Hammershøj, Anne Raben, Hanne Christine Bertram

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03656367 (Designing Biofunctional Dairy Foods), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03656367 nacompletednot on this map

Designing Biofunctional Dairy Foods: Matrix Structure of Dairy Products in Relation to Lipaemia

TypeinterventionalSponsorAnne Birgitte RabenRan2018 to 2019Enrolled25ConditionsLipaemiaArmsCheddar cheese, Blended and homogenized cheddar cheese, An analog milk, An analog cheese
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rebekka ThøgersenDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.
Ida Emilie I LindahlDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.
Bekzod KhakimovDepartment of Food Science, University of Copenhagen, DK-1958 Frederiksberg C, Denmark.ORCID 0000-0002-6580-2034
Louise KjølbækDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, Denmark.
Klaus Juhl JensenArla Foods Amba, DK-8200 Aarhus N, Denmark.
Arne AstrupDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, Denmark.ORCID 0000-0001-8968-8996
Marianne HammershøjDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.ORCID 0000-0001-9297-6526
Anne RabenDepartment of Nutrition, Exercise and Sports, University of Copenhagen, DK-1958 Frederiksberg C, Denmark.ORCID 0000-0001-5229-4491
Hanne Christine BertramDepartment of Food Science, Aarhus University, Agro Food Park 48, DK-8200 Aarhus N, Denmark.ORCID 0000-0002-1882-5321
Aarhus University · DKUniversity of Copenhagen · DKArla Foods (Denmark) · DK

Funding

Arla Food for Health, Denmark None
6 · The paper itself

Abstract

Studies have indicated that the dairy matrix can affect postprandial responses of dairy products, but little is known about the effect on postprandial plasma phospholipid levels. This study investigated postprandial plasma phospholipid levels following consumption of four different dairy products that are similar in micro and macro nutrients, but different in texture and structure: cheddar cheese (Cheese), homogenized cheddar cheese (Hom. Cheese), micellar casein isolate with cream (MCI Drink) or a gel made from the MCI Drink (MCI Gel). The study was an acute randomized, crossover trial in human volunteers with four test days. Blood samples were collected during an 8 h postprandial period and the content of 53 plasma phospholipids was analysed using liquid chromatography-mass spectrometry (LC-MS). No meal-time interactions were revealed; however, for nine of the 53 phospholipids, a meal effect was found. Thus, the results indicated a lower plasma level of specific lyso-phosphatidylethanolamines (LPEs) and lyso-phosphatidylcholines (LPCs) following consumption of the MCI Gel compared to the MCI Drink and Hom. Cheese, which might be attributed to an effect of viscosity. However, further studies are needed in order to reveal more details on the effect of the dairy matrix on postprandial phospholipids.

Indexed as

caseincheesefood structuremilk phospholipidsphospholipidomics

Identifiers

PMID34357348
PMCPMC8307057
OpenAlexW3179479132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.