ArticleMetabolites2021
Hyperpolarized Dihydroxyacetone Is a Sensitive Probe of Hepatic Gluconeogenic State.
Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- Hyperpolarized [2-ACS sensors · 2024Article
- Observing exocrine pancreas metabolism using a novel pancreas perfusion technique in combination with hyperpolarized [1-Magnetic resonance in chemistry : MRC · 2023Article
- Enrichment of hepatic glycogen and plasma glucose from H₂NMR in biomedicine · 2023Article
- Magnetic Resonance Imaging and Spectroscopy Methods to Study Hepatic Glucose Metabolism and Their Applications in the Healthy and Diabetic Liver.Metabolites · 2022Review
- Solution Chemistry of Dihydroxyacetone and Synthesis of Monomeric Dihydroxyacetone.Chemical research in toxicology · 2022Article
- Ex Vivo Hepatic Perfusion Through the Portal Vein in Mouse.Journal of visualized experiments : JoVE · 2022Article
- DetectingFrontiers in physiology · 2022Article
- Non-Invasive Analysis of Human Liver Metabolism by Magnetic Resonance Spectroscopy.Metabolites · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished only via tracer metabolism approaches that rely on multiple assumptions, and are clinically intractable due to expense and time needed for the studies. We previously introduced hyperpolarized (HP) [2-
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.