ArticleJournal of personalized medicine2021
Association of Ventilatory Disorders with Respiratory Symptoms, Physical Activity, and Quality of Life in Subjects with Prior Tuberculosis: A National Database Study in Korea.
Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The trial behind it
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- Trends of Electronic-Cigarette and Heated Tobacco Product Use Among Korean Adults From 2013 to 2023: A Cross-Sectional Study.Journal of Korean medical science · 2026Article
- Persistent Airflow Limitation in Asthma: Clinical Characteristics, Risk Factors, and Long-term Outcomes from a Multicenter Cohort Study.Journal of asthma and allergy · 2026Article
- Influenza Vaccination Trends and Associated Factors Among Middle-aged Working Adults With an Elevated Cardiovascular Risk in Korea.Korean circulation journal · 2025Article
- Bronchiectasis in Asia: a review of current status and challenges.European respiratory review : an official journal of the European Respiratory Society · 2024Review
- Prevalence of and factors associated with likely obstructive sleep apnea in individuals with airflow limitation.Frontiers in medicine · 2024Article
- Impaired pulmonary function and associated factors in the elderly with tuberculosis on admission: a preliminary report.BMC infectious diseases · 2023Article
- Personalized Medicine in Epidemics.Journal of personalized medicine · 2022Article
- Review
- Secular trends and determinants of influenza vaccination uptake among patients with cardiovascular disease in Korea: Analysis using a nationwide database.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tuberculosis (TB) survivors experience post-TB lung damage and ventilatory function disorders. However, the proportions of obstructive and restrictive ventilatory disorders as well as normal ventilation among subjects with prior TB are unknown. In addition, the impacts of ventilatory disorder and its severity on respiratory symptoms, physical activity limitations, and the quality of life in subjects with prior TB remain unclear. Subjects who participated in the Korean National Health and Nutritional Examination Survey 2007-2016 were enrolled in this study. We evaluated the impact of each ventilatory disorder and its severity on respiratory symptoms, physical activity limitations, and quality of life (measured by the EuroQoL five dimensions questionnaire [EQ-5D] index values) in subjects with prior TB. Among 1466 subjects with prior TB, 29% and 16% had obstructive ventilatory disorders and restrictive ventilatory disorders, respectively. Mild and moderate obstructive ventilatory disorders were not associated with respiratory symptoms, physical activity limitations, or EQ-5D index value compared with normal ventilation; however, severe obstructive ventilatory disorders were associated with more respiratory symptoms (adjusted odds ratio [aOR] = 13.62, 95% confidence interval [CI] = 4.64-39.99), more physical activity limitation (aOR = 218.58, 95% CI = 26.82-1781.12), and decreased EQ-5D index (adjusted coefficient = -0.06, 95% CI = (-0.12--0.10) compared with normal ventilation. Mild restrictive ventilatory disorders were associated with more respiratory symptoms (aOR = 2.10, 95% CI = 1.07-4.14) compared with normal ventilation, while moderate (aOR = 5.71, 95% CI = 1.14-28.62) and severe restrictive ventilatory disorders (aOR = 9.17, 95% CI = 1.02-82.22) were associated with physical activity limitation compared with normal ventilation. In conclusion, among subjects with prior TB, 29% and 16% developed obstructive and restrictive ventilatory disorders, respectively. Severe obstructive ventilatory disorder was associated with more respiratory symptoms, more physical activity limitation, and poorer quality of life, while severe restrictive ventilatory disorder was associated with more physical activity limitations.
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