Evidence map›Paper›PMID 34357142›Full record

ArticleJournal of personalized medicine2021

Individualized Prognostic Prediction of the Long-Term Functional Trajectory in Pediatric Acquired Brain Injury.

Erika Molteni, Marta Bianca Maria Ranzini, Elena Beretta, Marc Modat, Sandra Strazzer

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erika MolteniSchool of Biomedical Engineering & Imaging Sciences, King's College London, London SE1 7EU, UK.ORCID 0000-0001-7773-8140
Marta Bianca Maria RanziniSchool of Biomedical Engineering & Imaging Sciences, King's College London, London SE1 7EU, UK.
Elena BerettaAcquired Brain Injury Unit, Scientific Institute IRCCS E. Medea, 22040 Bosisio Parini, Italy.ORCID 0000-0002-8036-7624
Marc ModatSchool of Biomedical Engineering & Imaging Sciences, King's College London, London SE1 7EU, UK.
Sandra StrazzerAcquired Brain Injury Unit, Scientific Institute IRCCS E. Medea, 22040 Bosisio Parini, Italy.ORCID 0000-0001-8414-6565

Funding

Medical Research Council Skills Development Fellowship SchemeWellcome Trust 203148/Z/16/Z
6 · The paper itself

Abstract

In pediatric acquired brain injury, heterogeneity of functional response to specific rehabilitation treatments is a key confound to medical decisions and outcome prediction. We aimed to identify patient subgroups sharing comparable trajectories, and to implement a method for the early prediction of the long-term recovery course from clinical condition at first discharge. 600 consecutive patients with acquired brain injury (7.4 years ± 5.2; 367 males; median GCS = 6) entered a standardized rehabilitation program. Functional Independent Measure scores were measured yearly, until year 7. We classified the functional trajectories in clusters, through a latent class model. We performed single-subject prediction of trajectory membership in cases unseen during model fitting. Four trajectory types were identified (post.prob. > 0.95): high-start fast (

Indexed as

acquired brain injury (ABI)Functional Independence Measure for children (WeeFIM)latent class analysismixed modelssingle-subject recovery predictionstructural equation modelling (SEM)trajectory prediction

Identifiers

PMID34357142
PMCPMC8305391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.