Evidence map›Paper›PMID 34357098›Full record

ArticleJournal of personalized medicine2021

Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer.

Emily P Slater, Lisa M Wilke, Lutz Benedikt Böhm, Konstantin Strauch, Manuel Lutz, Norman Gercke, Elvira Matthäi, Kari Hemminki, Asta Försti, Matthias Schlesner and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Emily P SlaterDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Lisa M WilkeDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Lutz Benedikt BöhmDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Konstantin StrauchInstitute of Medical Biometry, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, D-55101 Mainz, Germany.
Manuel LutzInstitute of Medical Biometry, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, D-55101 Mainz, Germany.
Norman GerckeDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Elvira MatthäiDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Kari HemminkiGerman Cancer Research Center (DKFZ), Division of Molecular Genetic Epidemiology, D-69120 Heidelberg, Germany.
Asta FörstiGerman Cancer Research Center (DKFZ), Division of Molecular Genetic Epidemiology, D-69120 Heidelberg, Germany.ORCID 0000-0002-9857-4728
Matthias SchlesnerBioinformatics and Omics Data Analytics, German Cancer Research Center, D-69120 Heidelberg, Germany.ORCID 0000-0002-5896-4086
Nagarajan ParamasivamComputational Oncology, Molecular Diagnostics Program, National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.
Detlef K BartschDepartment of Visceral, Thoracic and Vascular Surgery, Philipps University, D-35043 Marburg, Germany.
Philipps University of Marburg · DEGerman Cancer Research Center · DEJohannes Gutenberg University Mainz · DEUniversity of Augsburg · DE

Funding

Deutsche Krebshilfe 111092GAUFF-Foundation 10001
6 · The paper itself

Abstract

Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma (PDAC) cases. No major causative gene defect has yet been identified, but germline mutations in predisposition genes

Indexed as

familial pancreatic cancergenetic variantsWGS

Identifiers

PMID34357098
PMCPMC8305658
OpenAlexW3176250615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.