Evidence map›Paper›PMID 34357097›Full record

ReviewJournal of personalized medicine2021

Personalized Therapy and Liquid Biopsy-A Focus on Colorectal Cancer.

Niki Christou, Léa Veyrune, Sotirios Georgios Popeskou, Muriel Mathonnet

Open access · goldAbstract readReview
In one paragraph

Review in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Niki ChristouDigestive Surgery Department, University Hospital of Limoges, 87000 Limoges, France.ORCID 0000-0003-2125-0503
Léa VeyruneService de Cytogénétique, Génétique Médicale et Biologie de la Reproduction, Univerity Hospital of Limoges, 87000 Limoges, France.ORCID 0000-0002-1604-8274
Sotirios Georgios PopeskouDepartment of Surgery, Regional Hospital of Lugano, 6900 Lugano, Switzerland.ORCID 0000-0001-8971-5624
Muriel MathonnetDigestive Surgery Department, University Hospital of Limoges, 87000 Limoges, France.
CNR de la Résistance aux Antibiotiques · FROspedale regionale di Lugano · CHQueen Elizabeth Hospital Birmingham · GBUniversité de Limoges · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Resistance mechanisms represent a barrier to anti-cancer therapies. Liquid biopsies would allow obtaining additional information in order to develop targeted therapies to thwart the resistance phenomena but also to follow in time real response to treatment and be able to adapt it the most quickly possible way in case of resistance. (2) Methods: herein we summarize the different liquid biopsies which are currently under research; we then review the literature and focalize on one of their potential roles: the theranostic one and especially in the cases of colorectal cancers. (3) Results: few studies targeting liquid biopsy as a potential tool to adapt cancer treatments are present in the literature and encompass few patients. (4) Conclusions: further research is needed to prove the efficiency of LB. Indeed, it seems a promising tool to guide treatment by targeting actionable mutations with detection of resistant mutations.

Indexed as

cancersliquid biopsypersonalized treatment

Identifiers

PMID34357097
PMCPMC8305103
OpenAlexW3176211077

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.