Evidence map›Paper›PMID 34357047›Full record

ArticleLife (Basel, Switzerland)2021

Exploring the Ability of LARS2 Carboxy-Terminal Domain in Rescuing the MELAS Phenotype.

Francesco Capriglia, Francesca Rizzo, Giuseppe Petrosillo, Veronica Morea, Giulia d'Amati, Palmiro Cantatore, Marina Roberti, Paola Loguercio Polosa, Francesco Bruni

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Human mtDNA-Encoded Long ncRNAs: Knotty Molecules and Complex Functions.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Mitochondrial DNA abnormalities and metabolic syndrome.Frontiers in cell and developmental biology · 2023
    Review
  7. Mitochondria: From Physiology to Pathology.Life (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Francesco CaprigliaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0001-7113-1276
Francesca RizzoDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0002-1736-8966
Giuseppe PetrosilloInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council (CNR), 70125 Bari, Italy.ORCID 0000-0001-8035-8368
Veronica MoreaInstitute of Molecular Biology and Pathology (IMBP), National Research Council (CNR), 00185 Rome, Italy.
Giulia d'AmatiDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6959-691X
Palmiro CantatoreDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.
Marina RobertiDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.
Paola Loguercio PolosaDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.
Francesco BruniDepartment of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari Aldo Moro, 70125 Bari, Italy.ORCID 0000-0001-5120-5936
University of Bari Aldo Moro · ITConsorzio Interuniversitario per le Biotecnologie · ITInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies · ITInstitute of Molecular Biology and Pathology · ITSapienza University of Rome · IT

Funding

AFM-Téléthon 20607Consorzio Interuniversitario Biotecnologie BIOS.ROBERTI.CIB.2020Universita degli Studi di Bari Aldo Moro Bruni11906Ricat15_16Universita degli Studi di Bari Aldo Moro Bruni11906Ricat17_18Universita degli Studi di Bari Aldo Moro Loguercio4523Ricat15_16
6 · The paper itself

Abstract

The m.3243A>G mutation within the mitochondrial mt-tRNALeu

Indexed as

aminoacyl-tRNA synthetasesCtermLARS2MELASmitochondrial diseasetherapeutic peptidestransmitochondrial cybrids

Identifiers

PMID34357047
PMCPMC8303833
OpenAlexW3177949657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.