Evidence map›Paper›PMID 34357035›Full record

ArticleLife (Basel, Switzerland)2021

Mitochondrial Genomic Landscape: A Portrait of the Mitochondrial Genome 40 Years after the First Complete Sequence.

Alessandro Formaggioni, Andrea Luchetti, Federico Plazzi

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
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  6. SmithRNAs: A Common Feature among Metazoa.Genome biology and evolution · 2025
    Article
  7. Morphology, Molecular Characterization, and Phylogeny ofAnimals : an open access journal from MDPI · 2025
    Article
  8. Article
  9. Typing ofFrontiers in microbiology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Comparative mitogenomic analysis ofFrontiers in physiology · 2024
    Article
  16. Characterization of the Complete Mitochondrial Genome ofInternational journal of molecular sciences · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alessandro FormaggioniDepartment of Biological, Geological and Environmental Sciences, University of Bologna, Via Selmi, 3, 40126 Bologna, BO, Italy.
Andrea LuchettiDepartment of Biological, Geological and Environmental Sciences, University of Bologna, Via Selmi, 3, 40126 Bologna, BO, Italy.ORCID 0000-0002-2986-721X
Federico PlazziDepartment of Biological, Geological and Environmental Sciences, University of Bologna, Via Selmi, 3, 40126 Bologna, BO, Italy.ORCID 0000-0001-5920-7557
University of Bologna · IT

Funding

Canziani Bequest A.31.CANZELSEWCanziani Bequest CANZIANI LUCHETTI
6 · The paper itself

Abstract

Notwithstanding the initial claims of general conservation, mitochondrial genomes are a largely heterogeneous set of organellar chromosomes which displays a bewildering diversity in terms of structure, architecture, gene content, and functionality. The mitochondrial genome is typically described as a single chromosome, yet many examples of multipartite genomes have been found (for example, among sponges and diplonemeans); the mitochondrial genome is typically depicted as circular, yet many linear genomes are known (for example, among jellyfish, alveolates, and apicomplexans); the chromosome is normally said to be "small", yet there is a huge variation between the smallest and the largest known genomes (found, for example, in ctenophores and vascular plants, respectively); even the gene content is highly unconserved, ranging from the 13 oxidative phosphorylation-related enzymatic subunits encoded by animal mitochondria to the wider set of mitochondrial genes found in jakobids. In the present paper, we compile and describe a large database of 27,873 mitochondrial genomes currently available in GenBank, encompassing the whole eukaryotic domain. We discuss the major features of mitochondrial molecular diversity, with special reference to nucleotide composition and compositional biases; moreover, the database is made publicly available for future analyses on the MoZoo Lab GitHub page.

Indexed as

compositional biasEukaryotamitochondrial genomemtDNA architecturemtDNA expansionmtDNA structurenucleotide compositionstrand asymmetry

Identifiers

PMID34357035
PMCPMC8303319
OpenAlexW3182682238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.