SynthesisMedicina (Kaunas, Lithuania)2021
Association of Thyroid Function with Suicidal Behavior: A Systematic Review and Meta-Analysis.
Synthesis in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 40 citations in OpenAlex.
- Determinants of Diabetic Peripheral Neuropathy and Their Clinical Significance: A Retrospective Cohort Study.Frontiers in endocrinology · 2022Trial
- Prevalence and Clinical Correlates of Suicide Attempts Among Young Patients With Major Depressive Disorder With Subclinical Hypothyroidism: A Cross-Sectional Study.Brain and behavior · 2026Article
- Characteristics of non-suicidal self-injury and its associations with thyroid and sex hormones in adolescents with major depressive disorder and bipolar disorder.BMC psychiatry · 2026Article
- Integrating neurobiological markers to prospectively predict adolescent non-suicidal self-injury and suicide attempts: a machine learning approach.Child and adolescent psychiatry and mental health · 2026Article
- Biomarkers associated with future suicide risk enhance predictive performance in psychiatric inpatients.BMJ health & care informatics · 2026Article
- Thyroid-stimulating hormone, fasting blood glucose and suicidal ideation in Chinese adolescents with major depressive disorder: a cross-sectional study.Frontiers in psychiatry · 2026Article
- Poisoning with Thyroid Hormones Used Illegally-Systematic Review.Pharmaceuticals (Basel, Switzerland) · 2025Review
- A biological phenotype of suicide attempt in adolescents with nonsuicidal self-injury: a machine-based learning approach.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Neuroendocrine abnormalities as predictors of suicidal ideation in bipolar disorder patients during depressive episodes: a cross-sectional study.BMC psychiatry · 2025Article
- Association of Sexual Dysfunction, Vitamin D, and Thyroid Levels with Suicidal Behavior Among Patients with Depressive Disorder: A Cross-sectional Study.Indian journal of psychological medicine · 2025Article
- Comprehensive view of suicide: A neuro-immune-endocrine approach.World journal of psychiatry · 2025Review
- Biological Basis for the Formation of Suicidal Behavior: A Review.Medical journal of the Islamic Republic of Iran · 2025Review
- Metabolomic Changes in Major Depressive Disorder Adolescent Females with or without Suicide Attempts.Current neuropharmacology · 2025Article
- Article
- Relationship between thyroid-stimulating hormone and blood lipids in patients with first-episode depression.BMC psychiatry · 2024Article
- Sex differences in correlates of suicide attempts in Chinese Han first-episode and drug-naïve major depressive disorder with comorbid subclinical hypothyroidism: A cross-sectional study.Brain and behavior · 2024Article
- Is the acquired hypothyroidism a risk factor for developing psychiatric disorders?Frontiers in psychiatry · 2024Review
- Prevalence and related factors of first-time suicide attempts in the past 14 days in Chinese adult patients with first-episode drug-naïve major depressive disorder.Frontiers in psychiatry · 2024Article
- Article
- Clinical characteristics of suicidal behavior in first hospitalization and drug-naïve patients with major depressive disorder.Annals of general psychiatry · 2023Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
Thyroid disease is a very common condition that influences the entire human body, including cognitive function and mental health. As a result, thyroid disease has been associated with multiple neuropsychiatric conditions. However, the relationship between thyroid dysfunction and suicide is still controversial. We conducted a systematic review and meta-analysis to describe the association of thyroid function with suicidal behavior in adults. We searched four data bases (MEDLINE, EMBASE, PsycINFO, and Scopus) from their inception to 20 July 2018. Studies that reported mean values and standard deviation (SD) of thyroid hormone levels [Thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), total thyroxine (TT4), and total triiodothyronine (TT3)] in patients with suicidal behavior compared with controls were included in this meta-analysis. The abstracts and papers retrieved with our search strategies were reviewed independently and in duplicate by four reviewers for assessment of inclusion criteria and data extraction, as well as for evaluation of risk of bias. Random-effects models were used in this meta-analysis to establish the mean difference on thyroid function tests between groups. Overall, 2278 articles were identified, and 13 studies met the inclusion criteria. These studies involved 2807 participants, including 826 participants identified with suicidal behavior. We found that patients with suicide behavior had lower levels of FT3 (-0.20 pg/mL;
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