Evidence map›Paper›PMID 34356982›Full record

ReviewMedicina (Kaunas, Lithuania)2021

Recognized and Potentially New Biomarkers-Their Role in Diagnosis and Prognosis of Cardiovascular Disease.

Weronika Bargieł, Katarzyna Cierpiszewska, Klara Maruszczak, Anna Pakuła, Dominika Szwankowska, Aleksandra Wrzesińska, Łukasz Gutowski, Dorota Formanowicz

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 33 citations in OpenAlex.

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  20. Cardiovascular Biomarkers: Lessons of the Past and Prospects for the Future.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Weronika BargiełFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Katarzyna CierpiszewskaFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Klara MaruszczakFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Anna PakułaFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Dominika SzwankowskaFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Aleksandra WrzesińskaFaculty of Medicine, Poznan University of Medical Sciences, 60-812 Poznan, Poland.
Łukasz GutowskiDepartment of Medical Chemistry and Laboratory Medicine, Poznan University of Medical Sciences, Rokietnicka 8, 60-806 Poznan, Poland.ORCID 0000-0002-5369-366X
Dorota FormanowiczDepartment of Medical Chemistry and Laboratory Medicine, Poznan University of Medical Sciences, Rokietnicka 8, 60-806 Poznan, Poland.ORCID 0000-0001-6691-3863
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis and its consequences are the leading cause of mortality in the world. For this reason, we have reviewed atherosclerosis biomarkers and selected the most promising ones for review. We focused mainly on biomarkers related to inflammation and oxidative stress, such as the highly sensitive C-reactive protein (hs-CRP), interleukin 6 (IL-6), and lipoprotein-associated phospholipase A2 (Lp-PLA2). The microRNA (miRNA) and the usefulness of the bone mineralization, glucose, and lipid metabolism marker osteocalcin (OC) were also reviewed. The last biomarker we considered was angiogenin (ANG). Our review shows that due to the multifactorial nature of atherosclerosis, no single marker is known so far, the determination of which would unambiguously assess the severity of atherosclerosis and help without any doubt in the prognosis of cardiovascular risk.

Indexed as

BiomarkersCardiovascular Diseases1-Alkyl-2-acetylglycerophosphocholine EsteraseAtherosclerosisC-Reactive ProteinHumansInterleukin-6OsteocalcinPrognosisRibonuclease, PancreaticRisk Factors1-Alkyl-2-acetylglycerophosphocholine EsteraseangiogeninBiomarkersC-Reactive ProteinIL6 protein, humanInterleukin-6OsteocalcinRibonuclease, Pancreaticangiogeninatherosclerosisbiomarkerscardiovascular diseasehsCRPIL-6inflammationLp-PAL2miRNAosteocalcinoxidative stress

Identifiers

PMID34356982
PMCPMC8305174
OpenAlexW3179695070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.