Evidence map›Paper›PMID 34356949›Full record

ReviewJournal of fungi (Basel, Switzerland)2021

Structurally Uncommon Secondary Metabolites Derived from Endophytic Fungi.

Humberto E Ortega, Daniel Torres-Mendoza, Zuleima Caballero E, Luis Cubilla-Rios

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 67 citations in OpenAlex.

  1. Chemical Constituents of the Endophytic FungusMolecules (Basel, Switzerland) · 2026
    Article
  2. Review
  3. Review
  4. IMA fungus · 2025
    Review
  5. Article
  6. PeerJ · 2025
    Article
  7. Isolation of the Endophytic FungusPlants (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Humberto E OrtegaLaboratory of Tropical Bioorganic Chemistry, Faculty of Natural, Exact Sciences and Technology, University of Panama, Panama City 0824, Panama.
Daniel Torres-MendozaLaboratory of Tropical Bioorganic Chemistry, Faculty of Natural, Exact Sciences and Technology, University of Panama, Panama City 0824, Panama.ORCID 0000-0002-3540-4238
Zuleima Caballero ECenter of Cellular and Molecular Biology of Diseases, Institute for Scientific Research and Technology Services (INDICASAT-AIP), Clayton 0843-01103, Panama.ORCID 0000-0003-4538-9489
Luis Cubilla-RiosLaboratory of Tropical Bioorganic Chemistry, Faculty of Natural, Exact Sciences and Technology, University of Panama, Panama City 0824, Panama.ORCID 0000-0003-1666-8948
Universidad de Panamá · PAInstituto de Investigaciones Científicas y Servicios de Alta Tecnología · PA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among microorganisms, endophytic fungi are the least studied, but they have attracted attention due to their high biological diversity and ability to produce novel and bioactive secondary metabolites to protect their host plant against biotic and abiotic stress. These compounds belong to different structural classes, such as alkaloids, peptides, terpenoids, polyketides, and steroids, which could present significant biological activities that are useful for pharmacological or medical applications. Recent reviews on endophytic fungi have mainly focused on the production of novel bioactive compounds. Here, we focus on compounds produced by endophytic fungi, reported with uncommon bioactive structures, establishing the neighbor net and diversity of endophytic fungi. The review includes compounds published from January 2015 to December 2020 that were catalogued as unprecedented, rare, uncommon, or possessing novel structural skeletons from more than 39 different genera, with

Indexed as

biological activityendophytic fungiuncommon secondary metabolites

Identifiers

PMID34356949
PMCPMC8308102
OpenAlexW3183501282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.