Evidence map›Paper›PMID 34356941›Full record

ArticleJournal of fungi (Basel, Switzerland)2021

Antifungal Siderophore Conjugates for Theranostic Applications in Invasive Pulmonary Aspergillosis Using Low-Molecular TAFC Scaffolds.

Joachim Pfister, Milos Petrik, Katerina Bendova, Barbara Matuszczak, Ulrike Binder, Matthias Misslinger, Alexander Kühbacher, Fabio Gsaller, Hubertus Haas, Clemens Decristoforo

Open access · goldAbstract read
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Radiometal chelators for infection diagnostics.Frontiers in nuclear medicine · 2023
    Article
  10. Genetic Engineering ofJournal of fungi (Basel, Switzerland) · 2022
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Joachim PfisterDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0001-5357-126X
Milos PetrikInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77200 Olomouc, Czech Republic.ORCID 0000-0003-1334-5916
Katerina BendovaInstitute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc, 77200 Olomouc, Czech Republic.ORCID 0000-0001-6681-0100
Barbara MatuszczakInstitute of Pharmacy/Pharmaceutical Chemistry, University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-4507-8739
Ulrike BinderInstitute of Hygiene & Medical Microbiology, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-2160-2903
Matthias MisslingerInstitute of Molecular Biology, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-6380-700X
Alexander KühbacherInstitute of Molecular Biology, Medical University of Innsbruck, A-6020 Innsbruck, Austria.
Fabio GsallerInstitute of Molecular Biology, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0002-9257-8648
Hubertus HaasInstitute of Molecular Biology, Medical University of Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-2472-9878
Clemens DecristoforoDepartment of Nuclear Medicine, Medical University Innsbruck, A-6020 Innsbruck, Austria.ORCID 0000-0003-0566-4036
Innsbruck Medical University · ATInstitute of Molecular and Translational Medicine · CZUniversität Innsbruck · AT

Funding

Austrian Science Fund FWF P 30924
6 · The paper itself

Abstract

Invasive pulmonary aspergillosis (IPA) is a life-threatening form of fungal infection, primarily in immunocompromised patients and associated with significant mortality. Diagnostic procedures are often invasive and/or time consuming and existing antifungals can be constrained by dose-limiting toxicity and drug interaction. In this study, we modified triacetylfusarinine C (TAFC), the main siderophore produced by the opportunistic pathogen

Indexed as

antifungalantifungal susceptibility testingAspergillus fumigatusinvasive pulmonary aspergillosisPET/CTsiderophoreTAFCtheranostics

Identifiers

PMID34356941
PMCPMC8304796
OpenAlexW3178750569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.