Evidence map›Paper›PMID 34356859›Full record

ArticleBiomedicines2021

Myeloid HIF1α Is Involved in the Extent of Orthodontically Induced Tooth Movement.

Christian Kirschneck, Nadine Straßmair, Fabian Cieplik, Eva Paddenberg, Jonathan Jantsch, Peter Proff, Agnes Schröder

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Christian KirschneckDepartment of Orthodontics, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.ORCID 0000-0001-9473-8724
Nadine StraßmairDepartment of Orthodontics, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.
Fabian CieplikDepartment of Operative Dentistry and Periodontology, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.ORCID 0000-0002-1750-7380
Eva PaddenbergDepartment of Orthodontics, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.
Jonathan JantschInstitute of Microbiology and Hygiene, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.
Peter ProffDepartment of Orthodontics, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.
Agnes SchröderDepartment of Orthodontics, University Medical Centre of Regensburg, D-93053 Regensburg, Germany.ORCID 0000-0001-6010-9831
University of Regensburg · DEInstitute of Medical Microbiology and Hygiene · DE

Funding

Deutsche Forschungsgemeinschaft KI2105/1-2
6 · The paper itself

Abstract

During orthodontic tooth movement, transcription factor hypoxia-inducible factor 1α (HIF1α) is stabilised in the periodontal ligament. While HIF1α in periodontal ligament fibroblasts can be stabilised by mechanical compression, in macrophages pressure application alone is not sufficient to stabilise HIF1α. The present study was conducted to investigate the role of myeloid HIF1α during orthodontic tooth movement. Orthodontic tooth movement was performed in wildtype and

Indexed as

HIF1αmacrophageorthodontic tooth movementµCT

Identifiers

PMID34356859
PMCPMC8301336
OpenAlexW3181156471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.