Evidence map›Paper›PMID 34356838›Full record

ReviewBiomedicines2021

Primary Soft Tissue Sarcoma of the Heart: An Emerging Chapter in Cardio-Oncology.

Pietro Scicchitano, Maria Chiara Sergi, Matteo Cameli, Marcelo H Miglioranza, Marco Matteo Ciccone, Marica Gentile, Camillo Porta, Marco Tucci

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Surgical Management of Primary and Metastatic Cardiac Malignancies: A 20-Year Single-Center Experience.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Minimally-Invasive Approach in the Setting of a Malignant Primary Cardiac Tumor.The Thoracic and cardiovascular surgeon reports · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Cardiac Sarcoma Presenting as Tamponade.Journal of community hospital internal medicine perspectives · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Pietro ScicchitanoCardiology Department, Hospital "F. Perinei", 70022 Altamura, Italy.ORCID 0000-0003-0471-0053
Maria Chiara SergiDepartment of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0002-3093-6841
Matteo CameliDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, 53100 Siena, Italy.ORCID 0000-0003-3872-8964
Marcelo H MiglioranzaCardiology Institute of Rio Grande do Sul, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre 90050-170, Brazil.ORCID 0000-0002-3314-9712
Marco Matteo CicconeCardiology Section, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, 70124 Bari, Italy.
Marica GentileDepartment of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy.
Camillo PortaDepartment of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy.
Marco TucciDepartment of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy.ORCID 0000-0003-4008-4897
University of Bari Aldo Moro · ITUniversidade Federal de Ciências da Saúde de Porto Alegre · BRUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary malignant cardiac tumors are rare, with a prevalence of about 0.01% among all cancer histotypes. At least 60% of them are primary soft tissue sarcomas of the heart (pSTS-h) that represent almost 1% of all STSs. The cardiac site of origin is the best way to classify pSTS-h as it is directly linked to the surgical approach for cancer removal. Indeed, histological differentiation should integrate the classification to provide insights into prognosis and survival expectancy of the patients. The prognosis of pSTS-h is severe and mostly influenced by the primary localization of the tumor, the difficulty in achieving complete surgical and pharmacological eradication, and the aggressive biological features of malignant cells. This review aims to provide a detailed literature overview of the most relevant issues on primary soft tissue sarcoma of the heart and highlight potential diagnostic and therapeutic future perspectives.

Indexed as

cardiac sarcomacardio-oncologydiagnosismolecular diagnosistreatment

Identifiers

PMID34356838
PMCPMC8301302
OpenAlexW3180965847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.