Evidence map›Paper›PMID 34356823›Full record

ArticleMarine drugs2021

Characterization of an α 4/7-Conotoxin LvIF from

Man Guo, Jinpeng Yu, Xiaopeng Zhu, Dongting Zhangsun, Sulan Luo

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Man GuoKey Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Jinpeng YuMedical School, Guangxi University, Nanning 530004, China.ORCID 0000-0002-4936-8637
Xiaopeng ZhuMedical School, Guangxi University, Nanning 530004, China.ORCID 0000-0001-8830-4954
Dongting ZhangsunKey Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.
Sulan LuoKey Laboratory of Tropical Biological Resources of Ministry of Education, Key Laboratory for Marine Drugs of Haikou, School of Life and Pharmaceutical Sciences, Hainan University, Haikou 570228, China.ORCID 0000-0002-9358-5970
Guangxi University · CNHainan University · CN

Funding

Major Science and Technology Project of Hainan Province ZDKJ2016002National Natural Science Foundation of China 81872794 and 41966003
6 · The paper itself

Abstract

Nicotinic acetylcholine receptor (nAChR), a member of pentameric ligand-gated ion channel transmembrane protein composed of five subunits, is widely distributed in the central and peripheral nervous system. The nAChRs are associated with various neurological diseases, including schizophrenia, Alzheimer's disease, Parkinson's disease, epilepsy and neuralgia. Receptors containing the α3 subunit are associated with analgesia, generating our interest in their role in pharmacological studies. In this study, α-conotoxin (α-CTx) LvIF was identified as a 16 amino acid peptide using a genomic DNA clone of

Indexed as

Conus SnailAnimalsConotoxinsNicotinic AntagonistsReceptors, NicotinicConotoxinsNicotinic Antagonistsnicotinic receptor alpha3beta2Receptors, Nicotinicrα3β2 nAChRtwo-electrode voltage clamptwo-step oxidationα-CTx LvIF

Identifiers

PMID34356823
PMCPMC8306566
OpenAlexW3183731140

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.