Evidence map›Paper›PMID 34356816›Full record

ArticleMarine drugs2021

Blue Biotechnology: Computational Screening of

Mahmoud A A Ibrahim, Alaa H M Abdelrahman, Mohamed A M Atia, Tarik A Mohamed, Mahmoud F Moustafa, Abdulrahim R Hakami, Shaden A M Khalifa, Fahad A Alhumaydhi, Faris Alrumaihi, Syed Hani Abidi and 6 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
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  10. Synthesis, X-ray diffraction analysis, quantum chemical studies andJournal of enzyme inhibition and medicinal chemistry · 2022
    Article
  11. ACS omega · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 8 countries.

Mahmoud A A IbrahimComputational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt.ORCID 0000-0003-4819-2040
Alaa H M AbdelrahmanComputational Chemistry Laboratory, Chemistry Department, Faculty of Science, Minia University, Minia 61519, Egypt.ORCID 0000-0003-3527-0126
Mohamed A M AtiaMolecular Genetics and Genome Mapping Laboratory, Genome Mapping Department, Agricultural Genetic Engineering Research Institute (AGERI), Agricultural Research Center (ARC), Giza 12619, Egypt.ORCID 0000-0003-2462-1269
Tarik A MohamedChemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt.ORCID 0000-0003-1639-3518
Mahmoud F MoustafaDepartment of Biology, College of Science, King Khalid University, Abha 9004, Saudi Arabia.
Abdulrahim R HakamiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha 61481, Saudi Arabia.ORCID 0000-0003-2101-8800
Shaden A M KhalifaDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden.
Fahad A AlhumaydhiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-0151-8309
Faris AlrumaihiDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-0850-5500
Syed Hani AbidiDepartment of Biological and Biomedical Sciences, Aga Khan University, Karachi 74800, Pakistan.ORCID 0000-0001-9497-0902
Khaled S AllemailemDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID 0000-0002-6486-9835
Thomas EfferthDepartment of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany.
Mahmoud E SolimanMolecular Modelling and Drug Design Research Group, School of Health Sciences, University of KwaZulu-Natal, Westville, Durban 4000, South Africa.
Paul W ParéDepartment of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA.ORCID 0000-0003-1644-723X
Hesham R El-SeediDepartment of Chemistry, Faculty of Science, El-Menoufia University, Shebin El-Kom 32512, Egypt.ORCID 0000-0002-2519-6690
Mohamed-Elamir F HegazyChemistry of Medicinal Plants Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza 12622, Egypt.ORCID 0000-0002-0343-4969
Qassim University · SAJohannes Gutenberg University Mainz · DEMinia University · EGAga Khan University · PKAgricultural Genetic Engineering Research Institute · EGJiangsu University · CNKing Khalid University · SANational Research Centre · EGSouth Valley University · EGStockholm University · SETexas Tech University · USUniversity of KwaZulu-Natal · ZA

Funding

King Khalid University R.G.P.1/143/42Science and Technology Development Fund 5480Science and Technology Development Fund 7972
6 · The paper itself

Abstract

The coronavirus pandemic has affected more than 150 million people, while over 3.25 million people have died from the coronavirus disease 2019 (COVID-19). As there are no established therapies for COVID-19 treatment, drugs that inhibit viral replication are a promising target; specifically, the main protease (M

Indexed as

COVID-19 Drug TreatmentAnimalsAnthozoaCoronavirus 3C ProteasesCoronavirus Protease InhibitorsCOVID-19DiterpenesHumansMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureSARS-CoV-2Structure-Activity RelationshipCoronavirus 3C ProteasesCoronavirus Protease InhibitorsDiterpenescembranoid diterpenes metabolitesgenus Sarcophytonmolecular dockingmolecular dynamicsreactomeSARS-CoV-2 main protease

Identifiers

PMID34356816
PMCPMC8308023
OpenAlexW3182784859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.