Evidence map›Paper›PMID 34356773›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Biosynthesis of Silver Nanoparticles Mediated by Entomopathogenic Fungi: Antimicrobial Resistance, Nanopesticides, and Toxicity.

Tárcio S Santos, Tarcisio M Silva, Juliana C Cardoso, Ricardo L C de Albuquerque-Júnior, Aleksandra Zielinska, Eliana B Souto, Patrícia Severino, Marcelo da Costa Mendonça

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Biosynthesized Silver Nanoparticles FromInternational journal of microbiology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Fabrication of Nano-Silver Composite UsingInternational journal of nanomedicine · 2025
    Article
  9. Article
  10. Review
  11. Natural antibiotics against antimicrobial resistance: sources and bioinspired delivery systems.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  12. Review
  13. Materials (Basel, Switzerland) · 2023
    Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Microbial silver resistance mechanisms: recent developments.World journal of microbiology & biotechnology · 2022
    Review
  19. Review
  20. Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Tárcio S SantosUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.
Tarcisio M SilvaUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.ORCID 0000-0002-9334-8959
Juliana C CardosoUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.
Ricardo L C de Albuquerque-JúniorUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.
Aleksandra ZielinskaFaculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Eliana B SoutoFaculty of Pharmacy, University of Coimbra, Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Patrícia SeverinoUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.ORCID 0000-0001-6527-6612
Marcelo da Costa MendonçaUniversity of Tiradentes (Unit), Av. Murilo Dantas, Aracaju 49010-390, Brazil.
Universidade Tiradentes · BRInstitute of Human Genetics · PLUniversity of Coimbra · PT

Funding

Coordination for the Improvement of Higher Education Personnel (Capes); Sergipe Agricultural Development Company (Emdagro); the Industrial Biotechnology Program, University Tiradentes, and by the Banco do Nordeste CAPES, Emdagro, BN
6 · The paper itself

Abstract

Silver nanoparticles are widely used in the biomedical and agri-food fields due to their versatility. The use of biological methods for the synthesis of silver nanoparticles has increased considerably due to their feasibility and high biocompatibility. In general, microorganisms have been widely explored for the production of silver nanoparticles for several applications. The objective of this work was to evaluate the use of entomopathogenic fungi for the biological synthesis of silver nanoparticles, in comparison to the use of other filamentous fungi, and the possibility of using these nanoparticles as antimicrobial agents and for the control of insect pests. In addition, the in vitro methods commonly used to assess the toxicity of these materials are discussed. Several species of filamentous fungi are known to have the ability to form silver nanoparticles, but few studies have been conducted on the potential of entomopathogenic fungi to produce these materials. The investigation of the toxicity of silver nanoparticles is usually carried out in vitro through cytotoxicity/genotoxicity analyses, using well-established methodologies, such as MTT and comet assays, respectively. The use of silver nanoparticles obtained through entomopathogenic fungi against insects is mainly focused on mosquitoes that transmit diseases to humans, with satisfactory results regarding mortality estimates. Entomopathogenic fungi can be employed in the synthesis of silver nanoparticles for potential use in insect control, but there is a need to expand studies on toxicity so to enable their use also in insect control in agriculture.

Indexed as

anti-microbialsbiological synthesisentomopathogenic fungiinsect controlsilver nanoparticles

Identifiers

PMID34356773
PMCPMC8300670
OpenAlexW3181445999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.