Evidence map›Paper›PMID 34356772›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Lower Respiratory Tract Pathogens and Their Antimicrobial Susceptibility Pattern: A 5-Year Study.

Biagio Santella, Enrica Serretiello, Anna De Filippis, Folliero Veronica, Domenico Iervolino, Federica Dell'Annunziata, Roberta Manente, Francesco Valitutti, Emanuela Santoro, Pasquale Pagliano and 3 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Prevalence and Antimicrobial Resistance ofInfectious disease reports · 2026
    Article
  4. Observational
  5. Correlation of type 3 secretion system genes with antimicrobial resistance inJournal of Taibah University Medical Sciences · 2026
    Article
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  9. Frontiers in microbiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Biagio SantellaSection of Microbiology and Virology, University Hospital "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5010-1390
Enrica SerretielloSection of Microbiology and Virology, University Hospital "Luigi Vanvitelli", 80138 Naples, Italy.
Anna De FilippisDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Folliero VeronicaSection of Microbiology and Virology, University Hospital "Luigi Vanvitelli", 80138 Naples, Italy.
Domenico IervolinoDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
Federica Dell'AnnunziataDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.
Roberta ManenteSection of Microbiology and Virology, University Hospital "Luigi Vanvitelli", 80138 Naples, Italy.
Francesco ValituttiClinical Pediatrics and Pediatrics, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.ORCID 0000-0002-1473-2240
Emanuela SantoroDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.
Pasquale PaglianoDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.
Massimiliano GaldieroSection of Microbiology and Virology, University Hospital "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-1576-6290
Giovanni BocciaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-7757-6855
Gianluigi FranciDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0003-3321-4331
University of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lower respiratory tract infections (LRTIs) are the most common infections in humans. It is estimated that 2.74 million deaths worldwide occur each year due to LRTIs. The aim of the study was to determine the frequency and antibiotic susceptibility pattern of microorganisms isolated from respiratory samples of patients with LRTIs. Between January 2015 and December 2019, a total of 7038 sputum and bronchoaspirate samples from suspected LRTI patients were collected. Among them, 2753 samples (39.1%) showed significant microbial growth on culture media. The LRTI rate was higher in patients with male gender (67.1%) and with age between 40-59 years (48.6%). The microorganism identification and antibiotic susceptibility testing were performed with Vitek 2. Out of 4278 isolates species, 3102 (72.5%) were Gram-negative bacteria, 1048 (24.5%) were Gram-positive bacteria, and 128 (3.0%) were

Indexed as

antimicrobial resistanceantimicrobial stewardshipepidemiologylower respiratory tract infectionsnosocomial infections

Identifiers

PMID34356772
PMCPMC8300710
OpenAlexW3182006782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.