Evidence map›Paper›PMID 34356724›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Benzothiazole-Containing Analogues of Triclocarban with Potent Antibacterial Activity.

Alessia Catalano, Antonio Rosato, Lara Salvagno, Domenico Iacopetta, Jessica Ceramella, Giuseppe Fracchiolla, Maria Stefania Sinicropi, Carlo Franchini

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Synthesis and crystal structure of ethyl 2-(1,3-benzo-thia-zol-2-yl)-1-oxo-1Acta crystallographica. Section E, Crystallographic communications · 2026
    Article
  3. Article
  4. Diarylureas: New Promising Small Molecules againstAntibiotics (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. Thidiazuron: New Trends and Future Perspectives to FightAntibiotics (Basel, Switzerland) · 2022
    Review
  9. Article
  10. Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alessia CatalanoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0002-7420-4706
Antonio RosatoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0001-5462-4650
Lara SalvagnoDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0002-8089-001X
Domenico IacopettaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0001-5179-7118
Jessica CeramellaDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0002-1386-3601
Giuseppe FracchiollaDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0003-4991-3962
Maria Stefania SinicropiDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Arcavacata di Rende, Italy.ORCID 0000-0003-2435-8931
Carlo FranchiniDepartment of Pharmacy-Drug Sciences, University of Bari "Aldo Moro", 70126 Bari, Italy.ORCID 0000-0002-3725-750X
University of Bari Aldo Moro · ITUniversity of Calabria · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca ex 60%
6 · The paper itself

Abstract

Triclocarban (TCC) is a polychlorinated, aromatic, antimicrobial agent commercially used since the 1950s in personal care products for the prevention of spoilage and infections. Humans are frequently exposed to TCC due to its widespread use, leading to its substantial release into the aquatic environment. With the recent ban of TCC from some personal care products, implemented in 2016, many replacement antimicrobial compounds have been studied by researchers. Herein, we report the synthesis and biological activity of a series of diarylureas, analogues of TCC that bear the benzothiazole nucleus as one of the two aryl moieties. Among the studied compounds,

Indexed as

antibacterial activitybenzothiazole derivativesdiarylureassmall moleculestriclocarban

Identifiers

PMID34356724
PMCPMC8300675
OpenAlexW3174699965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.