ArticleBiomolecules2021
Systematic Structure-Based Search for Ochratoxin-Degrading Enzymes in Proteomes from Filamentous Fungi.
Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- Unravelling the Role of Non-Clustered Polyketide Synthases and Key Metabolites in Ochratoxin a Accumulation byInternational journal of molecular sciences · 2026Article
- Microbial Detoxification of Ochratoxin A in Food.Foods (Basel, Switzerland) · 2026Review
- Detoxification of Ochratoxin a byToxins · 2026Article
- From the bench to the reactor: engineered filamentous fungi for biochemical and biomaterial production.Biotechnology for biofuels and bioproducts · 2025Review
- Fungal metabolite Ochratoxin A inhibits MrkD1P of multidrug-resistant Klebsiella pneumoniae: Integrated computational and in vitro validation.Journal of computer-aided molecular design · 2025Article
- Metarhizium spp. encode an ochratoxin cluster and a high efficiency ochratoxin-degrading amidohydrolase revealed by genomic analysis.Journal of advanced research · 2025Article
- Structural Similarity, Activity, and Toxicity of Mycotoxins: Combining Insights from Unsupervised and Supervised Machine Learning Algorithms.Journal of agricultural and food chemistry · 2025Article
- Considerations for Domestication of Novel Strains of Filamentous Fungi.ACS synthetic biology · 2025Review
- Negative Effects of Occurrence of Mycotoxins in Animal Feed and Biological Methods of Their Detoxification: A Review.Molecules (Basel, Switzerland) · 2024Review
- Article
- Whole genome analysis, detoxification of ochratoxin a and physiological characterization of a novelFrontiers in microbiology · 2024Article
- Degradation of ochratoxins A and B by lipases: A kinetic study unraveled by molecular modeling.Heliyon · 2023Article
- High-pressure acidified steaming with varied citric acid dosing can successfully detoxify mycotoxins.Food science & nutrition · 2023Article
- Molecular Docking and In Vitro Studies of Ochratoxin A (OTA) Biodetoxification Testing Three Endopeptidases.Molecules (Basel, Switzerland) · 2023Article
- Bio-control on the contamination of Ochratoxin A in food: Current research and future prospects.Current research in food science · 2022Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) Background: ochratoxins are mycotoxins produced by filamentous fungi with important implications in the food manufacturing industry due to their toxicity. Decontamination by specific ochratoxin-degrading enzymes has become an interesting alternative for the treatment of contaminated food commodities. (2) Methods: using a structure-based approach based on homology modeling, blind molecular docking of substrates and characterization of low-frequency protein motions, we performed a proteome mining in filamentous fungi to characterize new enzymes with potential ochratoxinase activity. (3) Results: the proteome mining results demonstrated the ubiquitous presence of fungal binuclear zinc-dependent amido-hydrolases with a high degree of structural homology to the already characterized ochratoxinase from
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Registered trials
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