Evidence map›Paper›PMID 34356661›Full record

ArticleBiomolecules2021

Identification of the Active Ingredient and Beneficial Effects of

Ji Hwan Lee, Sullim Lee, Quynh Nhu Nguyen, Hung Manh Phung, Myoung-Sook Shin, Jae-Yong Kim, Hyukjae Choi, Sang Hee Shim, Ki Sung Kang

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Anti-Menopausal Effect of Heat-KilledJournal of microbiology and biotechnology · 2024
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ji Hwan LeeCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Sullim LeeDepartment of Life Science, College of Bio-Nano Technology, Gachon University, Seongnam 13120, Korea.ORCID 0000-0002-4187-2177
Quynh Nhu NguyenCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.ORCID 0000-0003-2553-3690
Hung Manh PhungCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.ORCID 0000-0003-4215-7471
Myoung-Sook ShinCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.ORCID 0000-0002-5103-437X
Jae-Yong KimCollege of Pharmacy, Duksung Women's University, Seoul 01369, Korea.
Hyukjae ChoiCollege of Pharmacy, Yeungnam University, Gyeongsan 38541, Korea.ORCID 0000-0002-7707-4767
Sang Hee ShimCollege of Pharmacy, Duksung Women's University, Seoul 01369, Korea.
Ki Sung KangCollege of Korean Medicine, Gachon University, Seongnam 13120, Korea.
Gachon University · KRDuksung Women's University · KRSeoul National University · KRYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estrogen replacement therapy is a treatment to relieve the symptoms of menopause. Many studies suggest that natural bioactive ingredients from plants resemble estrogen in structure and biological functions and can relieve symptoms of menopause. The fruit of

Indexed as

AnimalsApigeninBiomarkersEstrogens, Non-SteroidalFemaleFlavonoidsFruitHumansMCF-7 CellsMedicine, Korean TraditionalMenopauseOvariectomyPlant ExtractsPlants, MedicinalRatsRats, Sprague-DawleyApigeninBiomarkerscasticinEstrogens, Non-SteroidalFlavonoidsPlant ExtractsvitexinE-screenMCF-7 cellmenopauseovariectomized ratVitex rotundifolia

Identifiers

PMID34356661
PMCPMC8301773
OpenAlexW3180157887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.