Evidence map›Paper›PMID 34356639›Full record

ReviewBiomolecules2021

Peroxidase Mimetic Nanozymes in Cancer Phototherapy: Progress and Perspectives.

Suresh Thangudu, Chia-Hao Su

Abstract readReview
In one paragraph

Review in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suresh ThanguduInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.ORCID 0000-0002-3124-9349
Chia-Hao SuInstitute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.ORCID 0000-0002-7441-448X

Funding

Chang Gung Medical Foundation, Taiwan CMRPG8I0141-3 and CMRPG8J0451-3Ministry of Science and Technology, Taiwan MOST 106-2314-B-182A-008-MY3, 109-2811-B-182A-527 and 109-2314-B-182A-011 -MY3
6 · The paper itself

Abstract

Nanomaterial-mediated cancer therapeutics is a fast developing field and has been utilized in potential clinical applications. However, most effective therapies, such as photodynamic therapy (PDT) and radio therapy (RT), are strongly oxygen-dependent, which hinders their practical applications. Later on, several strategies were developed to overcome tumor hypoxia, such as oxygen carrier nanomaterials and oxygen generated nanomaterials. Among these, oxygen species generation on nanozymes, especially catalase (CAT) mimetic nanozymes, convert endogenous hydrogen peroxide (H

Indexed as

AnimalsBiomimetic MaterialsHumansNanostructuresNeoplasmsOxygenPeroxidasePhotochemotherapyTumor HypoxiaTumor MicroenvironmentOxygenPeroxidasecancer therapydual enzymeenzyme mimeticnanomaterialsnanozymesperoxidase mimeticphototherapysingle atomtheranostics

Identifiers

PMID34356639
PMCPMC8301984

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.