Evidence map›Paper›PMID 34356625›Full record

ArticleBiomolecules2021

Monoamine Oxidase Inhibition by Major Tanshinones from

Ritu Prajapati, Se Eun Park, Su Hui Seong, Pradeep Paudel, Fazlin Mohd Fauzi, Hyun Ah Jung, Jae Sue Choi

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. In Vitro Screening ofInternational journal of molecular sciences · 2026
    Article
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  4. Hydroethanolic Extract ofTheScientificWorldJournal · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Ritu PrajapatiDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.ORCID 0000-0001-6862-1901
Se Eun ParkDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.
Su Hui SeongDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.
Pradeep PaudelDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.ORCID 0000-0001-8482-1129
Fazlin Mohd FauziDepartment of Pharmacology and Chemistry, Faculty of Pharmacy, Universiti Teknologi MARA, Puncak Alam 42300, Malaysia.ORCID 0000-0002-1572-9449
Hyun Ah JungDepartment of Food Science and Human Nutrition, Jeonbok National University, Jeonju 54896, Korea.
Jae Sue ChoiDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.ORCID 0000-0001-9034-8868
Pukyong National University · KRAsan Medical Center · KRJeonbuk National University · KRUniversiti Teknologi MARA · MYUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoamine oxidases (MAOs) and muscarinic acetylcholine receptors (mAChRs) are considered important therapeutic targets for Parkinson's disease (PD). Lipophilic tanshinones are major phytoconstituents in the dried roots of

Indexed as

AbietanesMonoamine OxidaseMonoamine Oxidase InhibitorsPhenanthrenesReceptor, Muscarinic M4AnimalsCHO CellsCricetulusHumansSalvia miltiorrhizaAbietanescryptotanshinoneMonoamine Oxidasemonoamine oxidase A, humanMonoamine Oxidase InhibitorsPhenanthrenesReceptor, Muscarinic M4tanshinoneM4 receptor antagonistmolecular dockingmonoamine oxidase inhibitionParkinson’s diseasetanshinone I

Identifiers

PMID34356625
PMCPMC8301926
OpenAlexW3179294507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.