Evidence map›Paper›PMID 34356558›Full record

ArticleChildren (Basel, Switzerland)2021

Impact of Graft Size Matching on the Early Post-Transplant Complications and Patients Survival in Children after Living Donor Liver Transplantations.

Marek Stefanowicz, Grzegorz Kowalewski, Marek Szymczak, Waldemar Patkowski, Krzysztof Zieniewicz, Ireneusz Grzelak, Adam Kowalski, Hor Ismail, Diana Kamińska, Piotr Kaliciński

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Marek StefanowiczDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.
Grzegorz KowalewskiDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.ORCID 0000-0001-7183-7711
Marek SzymczakDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.
Waldemar PatkowskiDepartment of General Surgery, Transplantation and Liver Surgery, Warsaw Medical University, 02-091 Warsaw, Poland.
Krzysztof ZieniewiczDepartment of General Surgery, Transplantation and Liver Surgery, Warsaw Medical University, 02-091 Warsaw, Poland.
Ireneusz GrzelakDepartment of General Surgery, Transplantation and Liver Surgery, Warsaw Medical University, 02-091 Warsaw, Poland.
Adam KowalskiDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.
Hor IsmailDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.
Diana KamińskaDepartment of Gastroenterology, Hepatology, Nutritional Disorders and Pediatrics, The Children's Memorial Health Institute, 04-730 Warszawa, Poland.
Piotr KalicińskiDepartment of Pediatric Surgery and Organ Transplantation, The Children's Memorial Health Institute Warsaw, 04-730 Warszawa, Poland.ORCID 0000-0003-0555-2229
Children's Memorial Health Institute · PLMedical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to assess the impact of the graft-recipient weight ratio (GRWR) on early post-transplant complications and patient survival rates in children after living donor liver transplantation (LDLT). We retrospectively analyzed 321 patients who underwent LDLT from 2004 to 2019. The recipients were categorized into four groups: 37 patients had a GRWR ≤ 1.5% (Group A), 196 patients had a GRWR > 1.5% and ≤3.5% (Group B), 73 patients had a GRWR > 3.5% and <5% (Group C) and 15 patients had a GRWR ≥ 5% (Group D). Incidence of early surgical complications including vascular complications, biliary complications, postoperative bleedings, gastrointestinal perforations and graft loss were comparable among groups with a different GRWR. Delayed abdominal wound closure was more common in patients with a GRWR > 3.5%. Recipients with a GRWR < 5% had a significantly better prognosis concerning patients and graft survival. Using grafts with a GRWR < 5% allows us to expand the donor pool and decrease the risk of mortality while on the waiting list, when patients at the time of transplantation have less advanced liver disease. LDLT with a GRWR ≥ 5% is related to a higher risk of poor outcome, and thus should be an option for treating selected patients when the risk of a delayed transplantation is high and access to deceased donors is limited.

Indexed as

graft to recipient weight ratioliver transplantationliving donor

Identifiers

PMID34356558
PMCPMC8307631
OpenAlexW3180667978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.