Evidence map›Paper›PMID 34356377›Full record

ArticleAntioxidants (Basel, Switzerland)2021

In Vitro Anticancer Activity and Oxidative Stress Biomarkers Status Determined by

Violeta Popovici, Laura Bucur, Gabriela Vochita, Daniela Gherghel, Cosmin Teodor Mihai, Dan Rambu, Suzana Ioana Calcan, Teodor Costache, Iulia Elena Cucolea, Elena Matei and 3 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Antimicrobial and cytotoxic activities of natural (Z)-13-docosenamide derived fromFrontiers in cellular and infection microbiology · 2025
    Article
  4. Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Implications of the Cultivation of Rosemary and Thyme (International journal of molecular sciences · 2023
    Article
  10. Article
  11. ROS-Induced DNA-Damage and Autophagy in Oral Squamous Cell Carcinoma byInternational journal of molecular sciences · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Pro-Apoptotic Potential ofPharmaceutics · 2021
    Article
  19. Editorial on Anticancer Antioxidants.Antioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Violeta PopoviciDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.ORCID 0000-0001-9696-5728
Laura BucurDepartment of Pharmacognosy, Faculty of Pharmacy, Ovidius University of Constanta, 6 Capitan Al. Serbanescu Street, 900001 Constanta, Romania.ORCID 0000-0002-7750-9871
Gabriela VochitaNIRDBS, Institute of Biological Research Iasi, 47 Lascar Catargi Street, 700107 Iasi, Romania.
Daniela GherghelNIRDBS, Institute of Biological Research Iasi, 47 Lascar Catargi Street, 700107 Iasi, Romania.
Cosmin Teodor MihaiNIRDBS, Institute of Biological Research Iasi, 47 Lascar Catargi Street, 700107 Iasi, Romania.ORCID 0000-0002-0945-5437
Dan RambuResearch Center for Instrumental Analysis SCIENT, 1E Petre Ispirescu Street, 077167 Tancabesti, Ilfov, Romania.
Suzana Ioana CalcanResearch Center for Instrumental Analysis SCIENT, 1E Petre Ispirescu Street, 077167 Tancabesti, Ilfov, Romania.
Teodor CostacheResearch Center for Instrumental Analysis SCIENT, 1E Petre Ispirescu Street, 077167 Tancabesti, Ilfov, Romania.ORCID 0000-0003-2116-4672
Iulia Elena CucoleaResearch Center for Instrumental Analysis SCIENT, 1E Petre Ispirescu Street, 077167 Tancabesti, Ilfov, Romania.
Elena MateiCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 145 Tomis Blvd., 900591 Constanta, Romania.
Florin Ciprian BadeaDepartment of Oral Rehabilitation, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.
Aureliana CaraianeDepartment of Oral Rehabilitation, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.
Victoria BadeaDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 7 Ilarie Voronca Street, 900684 Constanta, Romania.

Funding

ANTREPRENORDOC, in the framework of Human Resources Development Operational Program 2014-2020, financed from the European Social Fund contract number 36355/23.05.2019 HRD OP /380/6/13 - SMIS Code: 123847.
6 · The paper itself

Abstract

Lichens represent an important resource for common traditional medicines due to their numerous metabolites that can exert diverse pharmacological activities including anticancer effects. To find new anticancer compounds with fewer side effects and low tumor resistance, a bioprospective study of

Indexed as

antioxidant enzymes activityCAL-27 cancer cellsclonogenesiscytotoxicityUsnea barbata dry extractsusnic acidV79 healthy cellswound healing assay

Identifiers

PMID34356377
PMCPMC8301184

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.