Evidence map›Paper›PMID 34356370›Full record

ArticleAntioxidants (Basel, Switzerland)2021

DNA Damage in Human Amniotic Cells: Antigenotoxic Potential of Curcumin and

Filomena Mottola, Marianna Santonastaso, Concetta Iovine, Cristina Rossetti, Valentina Ronga, Lucia Rocco

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Effect of Oxidative Stress on Reproduction and Development.Antioxidants (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Filomena MottolaDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Marianna SantonastasoDepartment of Woman, Child and General and Special Surgery, University of Campania, Luigi Vanvitelli, 80138 Napoli, Italy.
Concetta IovineDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.
Cristina RossettiLaboratory of Animal Cytogenetics and Genomics, National Research Council (CNR), ISPAAM, 80055 Napoli, Italy.
Valentina RongaPrenatal Diagnosis Unit, Varelli Diagnostic Institute, 80126 Napoli, Italy.
Lucia RoccoDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, University of Campania Luigi Vanvitelli, 81100 Caserta, Italy.ORCID 0000-0001-6250-4798
University of Campania "Luigi Vanvitelli" · ITIstituto per il Sistema Produzione Animale in Ambiente Mediterraneo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative imbalances in the gestational phase are responsible for certain complications during pregnancy and for foetal and neonatal genetic disorders. In this work, using human amniocytes, we aimed to evaluate the protection provided to foetal DNA by two concentrations of antioxidant molecules, α-lipoic acid (LA) and curcumin (Cur), against hydrogen peroxide (H

Indexed as

antigenotoxicityantioxidantscurcuminDNA damagehuman amniocytesoxidative stressα-lipoic acid

Identifiers

PMID34356370
PMCPMC8301061
OpenAlexW3186104479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.