Evidence map›Paper›PMID 34356304›Full record

ArticleAntioxidants (Basel, Switzerland)2021

Anti-Oxidant and Anti-Inflammatory Substance Generated Newly in Paeoniae Radix Alba Extract Fermented with Plant-Derived

Shrijana Shakya, Narandalai Danshiitsoodol, Sachiko Sugimoto, Masafumi Noda, Masanori Sugiyama

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Tri-Culture Fermentation of Neem (Plants (Basel, Switzerland) · 2026
    Article
  2. Fermentation-Derived 6-Shogaol fromInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Stevia Leaf Extract Fermented with Plant-DerivedInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
  9. Chloroform Extract from FermentedJournal of microbiology and biotechnology · 2024
    Article
  10. Review
  11. Review
  12. Antibacterial Activities of Phenolic Compounds inAntibiotics (Basel, Switzerland) · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. The Role and Mechanism ofMolecules (Basel, Switzerland) · 2024
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shrijana ShakyaDepartment of Probiotic Science for Preventive Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
Narandalai DanshiitsoodolDepartment of Probiotic Science for Preventive Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.ORCID 0000-0002-9524-3667
Sachiko SugimotoDepartment of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
Masafumi NodaDepartment of Probiotic Science for Preventive Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
Masanori SugiyamaDepartment of Probiotic Science for Preventive Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan.
Hiroshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fermentation of medicinal herbs can be a significant technique to obtain bioactive compounds. Paeoniae Radix (PR) used in the present study is a well-known herbal medicine that exhibits anti-inflammatory and immunomodulatory activity. The aim of this study is to explore the possibility that a bioactive compound is newly generated in PR extract by fermentation with a plant-derived lactic acid bacteria

Indexed as

anti-inflammatoryantioxidantLactobacillus brevisPaeonia RadixpyrogallolRAW 264.7 macrophage cells

Identifiers

PMID34356304
PMCPMC8300999
OpenAlexW3178784498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.