Evidence map›Paper›PMID 34356292›Full record

ReviewHealthcare (Basel, Switzerland)2021

Role of Laboratory Medicine in SARS-CoV-2 Diagnostics. Lessons Learned from a Pandemic.

Irena Duś-Ilnicka, Aleksander Szymczak, Małgorzata Małodobra-Mazur, Miron Tokarski

Open access · goldAbstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Irena Duś-IlnickaGenomtec S.A., ul. Stabłowicka 147, 54-066 Wrocław, Poland.ORCID 0000-0002-4745-2560
Aleksander SzymczakGenomtec S.A., ul. Stabłowicka 147, 54-066 Wrocław, Poland.
Małgorzata Małodobra-MazurGenomtec S.A., ul. Stabłowicka 147, 54-066 Wrocław, Poland.
Miron TokarskiGenomtec S.A., ul. Stabłowicka 147, 54-066 Wrocław, Poland.
Wroclaw Medical University · PLLudwik Hirszfeld Institute of Immunology and Experimental Therapy · PL

Funding

Narodowe Centrum Badań i Rozwoju POIR.01.01.01-00-0669/20
6 · The paper itself

Abstract

Since the 2019 novel coronavirus outbreak began in Wuhan, China, diagnostic methods in the field of molecular biology have been developing faster than ever under the vigilant eye of world's research community. Unfortunately, the medical community was not prepared for testing such large volumes or ranges of biological materials, whether blood samples for antibody immunological testing, or salivary/swab samples for real-time PCR. For this reason, many medical diagnostic laboratories have made the switch to working in the field of molecular biology, and research undertaken to speed up the flow of samples through laboratory. The aim of this narrative review is to evaluate the current literature on laboratory techniques for the diagnosis of SARS-CoV-2 infection available on pubmed.gov, Google Scholar, and according to the writers' knowledge and experience of the laboratory medicine. It assesses the available information in the field of molecular biology by comparing real-time PCR, LAMP technique, RNA sequencing, and immunological diagnostics, and examines the newest techniques along with their limitations for use in SARS-CoV-2 diagnostics.

Indexed as

COVID-19LAMP assayreal-time polymerase chain reactionSARS-CoV-2

Identifiers

PMID34356292
PMCPMC8303636
OpenAlexW3185501750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.