Evidence map›Paper›PMID 34356274›Full record

ArticleHealthcare (Basel, Switzerland)2021

A Greek Validation Study of the Multiple Sclerosis Work Difficulties Questionnaire-23.

Christos Bakirtzis, Artemios Artemiadis, Elli Nteli, Marina Kleopatra Boziki, Maria-Valeria Karakasi, Cynthia Honan, Lambros Messinis, Grigorios Nasios, Efthimios Dardiotis, Nikolaos Grigoriadis

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christos BakirtzisMultiple Sclerosis Center, Second Department of Neurology, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece.ORCID 0000-0002-4737-3707
Artemios ArtemiadisFaculty of Medicine, University of Cyprus, Nicosia CY 2029, Cyprus.
Elli NteliMultiple Sclerosis Center, Second Department of Neurology, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece.
Marina Kleopatra BozikiMultiple Sclerosis Center, Second Department of Neurology, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece.ORCID 0000-0002-6601-5163
Maria-Valeria KarakasiThird University Department of Psychiatry, AHEPA University General Hospital, GR 54124 Thessaloniki, Greece.
Cynthia HonanSchool of Psychological Sciences, College of Health and Medicine, University of Tasmania, TAS 7250 Launceston, Australia.ORCID 0000-0001-5735-4270
Lambros MessinisNeuropsychology Section, University Hospital of Patras, GR 26504 Patras, Greece.
Grigorios NasiosDepartment of Speech and Language Therapy, University of Ioannina, GR 45110 Ioannina, Greece.ORCID 0000-0001-7495-6863
Efthimios DardiotisDepartment of Neurology, University of Thessaly, GR 41500 Larisa, Greece.ORCID 0000-0003-2957-641X
Nikolaos GrigoriadisMultiple Sclerosis Center, Second Department of Neurology, Aristotle University of Thessaloniki, GR 54124 Thessaloniki, Greece.ORCID 0000-0002-4278-3301

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23) is a self-report instrument developed to assess barriers faced by People with Multiple Sclerosis (PwMS) in the workplace. The aim of this study was to explore the psychometric properties of the Greek version of the MSWDQ-23. The study sample consisted of 196 PwMS, all currently working in part- or full-time jobs. Participants underwent clinical examination and cognitive screening with the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) and completed self-report measures of fatigue, psychological functioning, and quality of life, along with the MSWDQ-23 questionnaire. Confirmatory Factor Analysis (CFA) was performed, and goodness-of-fit measures were used to evaluate construct validity. Convergent validity was checked by correlating MSWDQ-23 scores with study measures. Cronbach's alpha value was produced to assess internal consistency. CFA yielded a model with a fair fit confirming the three-factor structure of the instrument. Higher work difficulties were associated with higher Expanded Disability Status Scale (EDSS) scores, poorer cognitive function, more fatigue, stress, anxiety, and depression, and poorer health status, supporting the convergent validity of MSWDQ-23. Internal consistency (Cronbach's alpha = 0.94) and test-retest reliability (ICC = 0.996, 95%, CI = 0.990-0.998) were excellent. The Greek MSWDQ-23 can be considered a valid patient-reported outcome measure and can be used in interventions aiming to improve the vocational status of PwMS.

Indexed as

employmentMSWDQ-23multiple sclerosispatient-reported outcomevalidation

Identifiers

PMID34356274
PMCPMC8306802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.