Evidence map›Paper›PMID 34356143›Full record

ArticleBrain sciences2021

Comparison of Functional Connectivity in the Prefrontal Cortex during a Simple and an Emotional Go/No-Go Task in Female versus Male Groups: An fNIRS Study.

Thien Nguyen, Emma E Condy, Soongho Park, Bruce H Friedman, Amir Gandjbakhche

Abstract read
In one paragraph

Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Gender and Smoking Pattern Differences in Behavioral Disinhibition.International journal of psychological research
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thien NguyenEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, 49 Convent Drive, Bethesda, MD 20814, USA.
Emma E CondyEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, 49 Convent Drive, Bethesda, MD 20814, USA.
Soongho ParkEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, 49 Convent Drive, Bethesda, MD 20814, USA.
Bruce H FriedmanDepartment of Psychology, Virginia Tech, 109 Williams Hall, Blacksburg, VA 24061, USA.
Amir GandjbakhcheEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, 49 Convent Drive, Bethesda, MD 20814, USA.ORCID 0000-0003-2652-0162

Funding

Functional and Structural Optical Brain ImagingZIAHD008882 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI GANDJBAKHCHE, AMIR H · 2009 to 2025
$11.4M
NIH HHS Intramural NICHD funds
6 · The paper itself

Abstract

Inhibitory control is a cognitive process to suppress prepotent behavioral responses to stimuli. This study aimed to investigate prefrontal functional connectivity during a behavioral inhibition task and its correlation with the subject's performance. Additionally, we identified connections that are specific to the Go/No-Go task. The experiment was performed on 42 normal, healthy adults who underwent a vanilla baseline and a simple and emotional Go/No-Go task. Cerebral hemodynamic responses were measured in the prefrontal cortex using a 16-channel near infrared spectroscopy (NIRS) device. Functional connectivity was calculated from NIRS signals and correlated to the Go/No-Go performance. Strong connectivity was found in both the tasks in the right hemisphere, inter-hemispherically, and the left medial prefrontal cortex. Better performance (fewer errors, faster response) is associated with stronger prefrontal connectivity during the simple Go/No-Go in both sexes and the emotional Go/No-Go connectivity in males. However, females express a lower emotional Go/No-Go connectivity while performing better on the task. This study reports a complete prefrontal network during a simple and emotional Go/No-Go and its correlation with the subject's performance in females and males. The results can be applied to examine behavioral inhibitory control deficits in population with neurodevelopmental disorders.

Indexed as

behavioral inhibitioncommission errorconnectivity–performance correlationemission errorinhibitory control deficitsresponse time

Identifiers

PMID34356143
PMCPMC8304823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.