Evidence map›Paper›PMID 34356109›Full record

ReviewGenes2021

Behind the Scene: Exploiting MC1R in Skin Cancer Risk and Prevention.

Michele Manganelli, Stefania Guida, Anna Ferretta, Giovanni Pellacani, Letizia Porcelli, Amalia Azzariti, Gabriella Guida

Open access · goldAbstract readReview
In one paragraph

Review in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

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  15. [MC1R is highly expressed in esophageal squamous cell carcinoma].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Michele ManganelliDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari-"Aldo Moro", 70125 Bari, Italy.ORCID 0000-0002-8219-0252
Stefania GuidaDepartment of Surgical-Medical-Dental and Morphological Science with Interest Transplant-Oncological and Regenerative Medicine, University of Modena and Reggio Emilia, 41124 Modena, Italy.
Anna FerrettaDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari-"Aldo Moro", 70125 Bari, Italy.ORCID 0000-0003-2279-9557
Giovanni PellacaniDepartment of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, 00161 Rome, Italy.
Letizia PorcelliLaboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.
Amalia AzzaritiLaboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, 70124 Bari, Italy.ORCID 0000-0002-6149-5049
Gabriella GuidaDepartment of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari-"Aldo Moro", 70125 Bari, Italy.
University of Bari Aldo Moro · ITIstituto Tumori Bari · ITSapienza University of Rome · ITUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma and non-melanoma skin cancers (NMSCs) are the most frequent cancers of the skin in white populations. An increased risk in the development of skin cancers has been associated with the combination of several environmental factors (i.e., ultraviolet exposure) and genetic background, including melanocortin-1 receptor (

Indexed as

Genetic Predisposition to DiseaseHumansMelanomaReceptor, Melanocortin, Type 1Risk FactorsSkinSkin NeoplasmsSkin Physiological PhenomenaReceptor, Melanocortin, Type 1basal cell carcinomaMC1Rmelanocortin 1 receptormelanomaskin cancer preventionsquamous cell

Identifiers

PMID34356109
PMCPMC8305013
OpenAlexW3184224771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.