Evidence map›Paper›PMID 34356103›Full record

ArticleGenes2021

Heterozygous

Lucie Šedová, Jan Prochazka, Dagmar Zudová, Běla Bendlová, Josef Včelák, Radislav Sedlacek, Ondřej Šeda

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. TheInternational journal of molecular sciences · 2025
    Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lucie ŠedováLaboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, 252 50 Vestec, Czech Republic.
Jan ProchazkaCzech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 252 50 Vestec, Czech Republic.
Dagmar ZudováCzech Centre for Phenogenomics, Institute of Molecular Genetics of the Czech Academy of Sciences, v.v.i., 252 50 Vestec, Czech Republic.
Běla BendlováDepartment of Molecular Endocrinology, Institute of Endocrinology, 116 94 Prague, Czech Republic.
Josef VčelákDepartment of Molecular Endocrinology, Institute of Endocrinology, 116 94 Prague, Czech Republic.
Radislav SedlacekLaboratory of Transgenic Models of Diseases, Division BIOCEV, Institute of Molecular Genetics of the Czech Academy of Sciences, 252 50 Vestec, Czech Republic.
Ondřej ŠedaInstitute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, and General University Hospital, 128 00 Prague, Czech Republic.ORCID 0000-0001-8498-5895
Czech Academy of Sciences · CZCharles University · CZInstitute of Endocrinology · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Complex metabolic conditions such as type 2 diabetes and obesity result from the interaction of numerous genetic and environmental factors. While the family of Nme proteins has been connected so far mostly to development, proliferation, or ciliary functions, several lines of evidence from human and experimental studies point to the potential involvement of one of its members, NME7 (non-metastatic cells 7, nucleoside diphosphate kinase 7) in carbohydrate and lipid metabolism. As a complete lack of

Indexed as

AdiposityAnimalsDiabetes Mellitus, Type 2DyslipidemiasGlucoseGlucose IntoleranceLipid MetabolismLipogenesisLiverMaleNucleoside-Diphosphate KinaseObesityRatsRats, Sprague-DawleyTranscriptomeGlucoseNME7 protein, humanNucleoside-Diphosphate Kinaseanimal modelsmetabolic syndromepancreatic fibrosis

Identifiers

PMID34356103
PMCPMC8305224
OpenAlexW3183446206

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.