Evidence map›Paper›PMID 34356074›Full record

ArticleGenes2021

Exposure to Fine Particulate Matter Air Pollution Alters mRNA and miRNA Expression in Bone Marrow-Derived Endothelial Progenitor Cells from Mice.

Xiaohong Li, Petra Haberzettl, Daniel J Conklin, Aruni Bhatnagar, Eric C Rouchka, Mei Zhang, Timothy E O'Toole

Open access · goldAbstract read
In one paragraph

Article in Genes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Airborne contaminant exposure and bone development: a systematic review and meta-analysis.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiaohong LiDepartment of Anatomical Sciences and Neurobiology, University of Louisville, Louisville, KY 40202, USA.
Petra HaberzettlChristina Lee Brown Envirome Institute, University of Louisville, Louisville, KY 40202, USA.
Daniel J ConklinChristina Lee Brown Envirome Institute, University of Louisville, Louisville, KY 40202, USA.
Aruni BhatnagarChristina Lee Brown Envirome Institute, University of Louisville, Louisville, KY 40202, USA.
Eric C RouchkaKentucky Biomedical Research Infrastructure Network Bioinformatics Core, University of Louisville, Louisville, KY 40202, USA.ORCID 0000-0003-3487-6572
Mei ZhangDepartment of Medicine, University of Louisville Genomics Facility, Louisville, KY 40202, USA.
Timothy E O'TooleChristina Lee Brown Envirome Institute, University of Louisville, Louisville, KY 40202, USA.ORCID 0000-0003-1773-1523
University of Louisville · US

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
University of Louisville Center for Integrative Environmental Health SciencesP30ES030283 · NIEHS · UNIVERSITY OF LOUISVILLE · PI Amanda Jo LeBlanc · 2020 to 2026
$10.0M
TBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI · 2018 to 2022
$6.3M
Endothelial Progenitor Cells and Particulate Air PollutionR01ES019217 · NIEHS · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI, O'TOOLE, TIMOTHY E · 2011 to 2022
$6.0M
Effects of Air Pollution on Stem Cell HealthR01ES028268 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HABERZETTL, PETRA, HILL, BRADFORD GUY · 2018 to 2022
$2.2M
Air Pollution, Circadian Rhythm Disruption and Cardiometabolic DiseaseR01ES027881 · NIEHS · UNIVERSITY OF LOUISVILLE · PI HABERZETTL, PETRA · 2017 to 2021
$1.7M
NIEHS NIH HHS P30 ES030283NIEHS NIH HHS R01 ES019217NIEHS NIH HHS R01 ES027881NIEHS NIH HHS R01 ES028268NIGMS NIH HHS P20 GM103436NIGMS NIH HHS P30 GM127607
6 · The paper itself

Abstract

Exposure to fine particulate matter (PM

Indexed as

Air PollutionAnimalsBone MarrowCell MovementCell ProliferationEndothelial Progenitor CellsGene Expression RegulationMaleMiceMice, Inbred C57BLMicroRNAsParticulate MatterRNA, MessengerMicroRNAsParticulate MatterRNA, Messengerair pollutioncardiovascular diseaseendothelial progenitor cell

Identifiers

PMID34356074
PMCPMC8307414
OpenAlexW3179921430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.