Evidence map›Paper›PMID 34355815›Full record

ArticleMagnetic resonance in medicine2022

Magnetic susceptibility and R2* of myocardial reperfusion injury at 3T and 7T.

Brianna F Moon, Srikant Kamesh Iyer, Nicholas J Josselyn, Eileen Hwuang, Sophia Swago, Samuel J Keeney, Estibaliz Castillero, Giovanni Ferrari, James J Pilla, Joseph H Gorman and 9 more

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Simultaneous 3-D Adiabatic TNMR in biomedicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Brianna F MoonDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-0642-0551
Srikant Kamesh IyerDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-6873-0294
Nicholas J JosselynDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Eileen HwuangDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sophia SwagoDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Samuel J KeeneyDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Estibaliz CastilleroDepartment of Surgery, Columbia University Irving Medical Center, New York City, New York, USA.
Giovanni FerrariDepartment of Surgery, Columbia University Irving Medical Center, New York City, New York, USA.
James J PillaDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph H GormanDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Robert C GormanDepartment of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Cory M TschabrunnDepartment of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Haochang ShouDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
William MatthaiDepartment of Medicine, Penn Presbyterian Medical Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Felix W WehrliDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3430-1840
Victor A FerrariDepartment of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Yuchi HanDepartment of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Harold LittDepartment of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Walter R WitscheyDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1669-2120
University of Pennsylvania · USColumbia University Irving Medical Center · USChildren's Hospital of Philadelphia · USPenn Presbyterian Medical Center · US

Funding

Multidisciplinary Training in Cardiovascular BiologyT32HL007954 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI DAVIES, PETER FRANCIS · 2000 to 2019
$9.9M
Supplement to Serotonin Signaling in Mitral Valve Homeostasis, Maintenance and RestorationR01HL131872 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI Giovanni Ferrari, Robert J Levy · 2016 to 2026
$7.7M
Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
Imaging-based Indentification of Premature Ventricular Contraction-mediatedR01HL148103 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HAN, YUCHI · 2020 to 2025
$2.8M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Role of RAGE in Bicuspid Aortic Valve SyndromeR01HL122805 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FERRARI, GIOVANNI · 2016 to 2019
$1.6M
Nuclear Magnetic Tirho Relaxation in Acute and Chronic Myocardial InfarctionsR00HL108157 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2014 to 2016
$747k
NHLBI NIH HHS R00 HL108157NHLBI NIH HHS R01 HL122805NHLBI NIH HHS R01 HL131872NHLBI NIH HHS R01 HL137984NHLBI NIH HHS R01 HL148103NHLBI NIH HHS T32 HL007954NIBIB NIH HHS T32 EB009384
6 · The paper itself

Abstract

purposeMagnetic susceptibility (Δχ) alterations have shown association with myocardial infarction (MI) iron deposition, yet there remains limited understanding of the relationship between relaxation rates and susceptibility or the effect of magnetic field strength. Hence, Δχ and

methodsSubacute MI was induced by coronary artery ligation in male Yorkshire swine. 3D multiecho gradient echo imaging was performed at 1-week postinfarction at 3T and 7T. Quantitative susceptibility mapping images were reconstructed using a morphology-enabled dipole inversion.

resultsMagnetic susceptibility was not significantly different across field strengths (7T: 126.8 ± 41.7 ppb; 3T: 110.2 ± 21.0 ppb, P = NS), unlike

conclusion

Indexed as

Magnetic Resonance ImagingMyocardial Reperfusion InjuryAnimalsIronMagnetic PhenomenaMagneticsMaleSwineIron7Themorrhageironmagnetic susceptibilitymyocardial infarction

Identifiers

PMID34355815
PMCPMC9067599
OpenAlexW3192604550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.