Evidence map›Paper›PMID 34355693›Full record

RevieweLife2021

The need for practical insecticide-resistance guidelines to effectively inform mosquito-borne disease control programs.

Alice Namias, Ndey Bassin Jobe, Krijn Petrus Paaijmans, Silvie Huijben

Abstract readReview
In one paragraph

Review in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

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  20. Resistance status ofNarra J · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alice NamiasDépartement de Biologie, Ecole Normale Supérieure, PSL Research University, Paris, France.ORCID 0000-0003-4590-2879
Ndey Bassin JobeCenter for Evolution and Medicine, School of Life Sciences, Arizona State University, Life Sciences C, Tempe, United States.
Krijn Petrus PaaijmansCenter for Evolution and Medicine, School of Life Sciences, Arizona State University, Life Sciences C, Tempe, United States.ORCID 0000-0003-4837-2818
Silvie HuijbenCenter for Evolution and Medicine, School of Life Sciences, Arizona State University, Life Sciences C, Tempe, United States.ORCID 0000-0002-3537-1915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring local mosquito populations for insecticide resistance is critical for effective vector-borne disease control. However, widely used phenotypic assays, which are designed to monitor the emergence and spread of insecticide resistance (technical resistance), do not translate well to the efficacy of vector control products to suppress mosquito numbers in the field (practical resistance). This is because standard testing conditions such as environmental conditions, exposure dose, and type of substrate differ dramatically from those experienced by mosquitoes under field conditions. In addition, field mosquitoes have considerably different physiological characteristics such as age and blood-feeding status. Beyond this, indirect impacts of insecticide resistance and/or exposure on mosquito longevity, pathogen development, host-seeking behavior, and blood-feeding success impact disease transmission. Given the limited number of active ingredients currently available and the observed discordance between resistance and disease transmission, we conclude that additional testing guidelines are needed to determine practical resistance-the efficacy of vector control tools under relevant local conditions- in order to obtain programmatic impact.

Indexed as

CulicidaeInsecticide ResistanceInsecticidesMosquito ControlMosquito VectorsAnimalsGuidelines as TopicVector Borne DiseasesInsecticidesAedesAnophelesepidemiologyevolutionary biologyglobal healthInsecticide resistancepolicysurveillancevector control

Identifiers

PMID34355693
PMCPMC8346280

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.