Evidence map›Paper›PMID 34355646›Full record

ArticlePlatelets2022

Severe thrombocytopenia in adults undergoing extracorporeal membrane oxygenation is predictive of thrombosis.

Tia C L Kohs, Patricia Liu, Vikram Raghunathan, Ramin Amirsoltani, Michael Oakes, Owen J T McCarty, Sven R Olson, Luke Masha, David Zonies, Joseph J Shatzel

Open access · greenAbstract read
In one paragraph

Article in Platelets, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Assessing Venous Thrombotic Risks in Extracorporeal Membrane Oxygenation-Supported Patients: A Systematic Review and Meta-Analysis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Pooled it
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  15. Platelet Function Testing to Guide Cangrelor Dosing in Patients with Temporary Mechanical Circulatory Support or as a Bridge to Procedure.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Tia C L KohsDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, USA.ORCID 0000-0002-7900-0016
Patricia LiuDepartment of Medicine, Oregon Health & Science University, Portland, USA.ORCID 0000-0002-0500-2465
Vikram RaghunathanDivision of Hematology and Oncology, Oregon Health & Science University, Portland, USA.ORCID 0000-0002-6026-4134
Ramin AmirsoltaniDepartment of Surgery, Oregon Health & Science University, Portland, USA.
Michael OakesDepartment of Medicine, Oregon Health & Science University, Portland, USA.
Owen J T McCartyDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, USA.ORCID 0000-0001-9481-0124
Sven R OlsonDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, USA.ORCID 0000-0002-2717-4620
Luke MashaDepartment of Cardiology, Oregon Health & Science University, Portland, USA.
David ZoniesDepartment of Cardiology, Oregon Health & Science University, Portland, USA.ORCID 0000-0002-8411-6187
Joseph J ShatzelDepartment of Biomedical Engineering, Oregon Health & Science University, Portland, USA.ORCID 0000-0001-9396-5976
Oregon Health & Science University · US

Funding

Characterization of Coagulation Factor-platelet Interactions: Role of FXIR01HL101972 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI Owen J McCarty · 2010 to 2026
$8.5M
Contact Pathway Activation on Vascular DevicesR01HL144113 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, MCCARTY, OWEN J · 2018 to 2025
$6.0M
Evaluating the Safety and Efficacy of Targeting the Contact Pathway to Prevent Device Associated Thrombosis.R01HL151367 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI SHATZEL, JOSEPH JAMES · 2020 to 2024
$1.5M
NHLBI NIH HHS R01 HL101972NHLBI NIH HHS R01 HL144113NHLBI NIH HHS R01 HL151367
6 · The paper itself

Abstract

Extracorporeal membrane oxygenation (ECMO) provides lifesaving circulatory support and gas exchange, although hematologic complications are frequent. The relationship between ECMO and severe thrombocytopenia (platelet count <50 × 10

Indexed as

Extracorporeal Membrane OxygenationThrombocytopeniaThrombosisAdultAnticoagulantsCohort StudiesHumansProspective StudiesRetrospective StudiesAnticoagulantsAnticoagulationECMOthrombocytopeniathrombosis

Identifiers

PMID34355646
PMCPMC9089832
OpenAlexW3187916071

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.