ArticleObesity (Silver Spring, Md.)2021
Reliability of measurements of energy expenditure and substrate oxidation using whole-room indirect calorimetry.
Article in Obesity (Silver Spring, Md.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Validity and Reliability of Resting Energy Expenditure Measured by Indirect Calorimetry in Adults with Overweight and Obesity: a Rapid Systematic Review.Obesity surgery · 2025Pooled it
- Effect of caloric restriction on organ size and its contribution to metabolic adaptation: an ancillary analysis of CALERIE 2.Scientific reports · 2025Trial
- Host-diet-gut microbiome interactions influence human energy balance: a randomized clinical trial.Nature communications · 2023Trial
- Glucagon-like peptide-1/glucagon receptor agonism associates with reduced metabolic adaptation and higher fat oxidation: A randomized trial.Obesity (Silver Spring, Md.) · 2023Trial
- Whole-Room Indirect Calorimetry in the Study of Obesity, Insulin Resistance and Metabolic Flexibility: A Narrative Review.Nutrients · 2026Review
- Running Distance Is Associated With Components of Total Energy Expenditure in Amenorrhoeic and Non-Amenorrhoeic Endurance Runners.Scandinavian journal of medicine & science in sports · 2026Article
- Effects of Glucagon-Like Peptide-1 Receptor Agonists (Mono and Combination Therapy) on Energy Expenditure: A Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Article
- Validity and reproducibility of a whole-room indirect calorimeter for measurement of the thermic effect of food.Physiological reports · 2026Article
- Evaluation of the effects of a new standard equation for doubly labeled water studies.Cell reports methods · 2026Article
- New insights into total and resting energy expenditure using state-of-the-art methods in cancer survivors: a cross-sectional study.The American journal of clinical nutrition · 2025Article
- Validation of a novel approach to assess metabolic flexibility to a high-fat meal in a whole-body room calorimeter.Obesity (Silver Spring, Md.) · 2025Article
- Energy expenditure and slow-wave sleep in runners: Focusing on reproductive function, chronic training, and sex.iScience · 2025Article
- Wearable microfluidic biosensors with haptic feedback for continuous monitoring of hydration biomarkers in workers.NPJ digital medicine · 2025Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveThis analysis aimed to measure the intraparticipant reliability-the intraclass correlation coefficient-of all the components of daily energy expenditure (EE) (24-hour EE, sleep EE, resting EE, basal EE, and thermic effect of food) over a period of 3 consecutive days in 35 study participants.
methodsThe components of daily EE and substrate use (respiratory exchange ratio) were measured over 3 consecutive days before and after a 3-week 1,000-kcal/d caloric restriction/weight-loss intervention.
resultsThere was a high degree of reliability for sleep EE (96.8%), 24-hour EE (97.8%), basal EE (90.6%), and resting EE (93.2%) during the run-in period. The intraclass correlation coefficient for the follow-up period after weight loss (3.67 ± 1.10 kg) remained high for sleep EE (95.6%), 24-hour EE (100%), basal EE (96.1%), and resting EE (92.5%). The minimal detectable differences in EE were reduced by 30% for both 24-hour EE and sleep EE when comparing 2 days versus 1 day spent in the whole-room indirect calorimeter.
conclusionsThe reliability of the daily components of EE is very high both prior to and after a weight-loss intervention. We here provide instrumental data for investigators to adequately power studies investigating energy metabolism using whole-room indirect calorimetry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.