ArticleThoracic cancer2021
Global burden of thyroid cancer and its attributable risk factors in 204 countries and territories from 1990 to 2019.
Article in Thoracic cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
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Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Dissecting the causal association of diet with thyroid cancer: a systematic review with meta-analysis and mendelian randomization analysis.Frontiers in nutrition · 2025Pooled it
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- Environmental Exposure Context and Advanced Stage at Diagnosis in Thyroid Cancer: A Population-Based SEER Analysis.Cancers · 2026Article
- Trends and cross-country inequalities in the global burden of thyroid cancer, 1990-2021: A population-based study.Medicine · 2026Article
- Ferroptosis induction by curcumin through regulating the expression of glutathione peroxidase 4 in papillary thyroid carcinoma.Journal of molecular histology · 2026Article
- Obesity as a risk factor for acute lymphoblastic leukemia in individuals younger than 20 years across 204 countries and territories from 1990 to 2021: a benchmarking global analysis.Annals of medicine and surgery (2012) · 2026Article
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- Thyroid cancer among children and adolescents aged 5-19 years from 1990 to 2021: a global, regional, and national perspective.Frontiers in oncology · 2026Article
- RoundupFrontiers in endocrinology · 2026Article
- TC check: a web app for thyroid cancer recurrence prediction using explainable machine learning.Journal of cancer research and clinical oncology · 2025Article
- Burden and trends of thyroid cancer among women of childbearing age, 1990-2021: A serial cross-sectional analysis.Medicine · 2025Article
- Burden of Breast Cancer and Its Attributable Risk Factors in the Belt and Road Initiative Countries, 1990-2021.Thoracic cancer · 2025Article
- Global burden and cross-country inequalities in head and neck cancer from 1992 to 2021: results from the global burden of disease study.Health economics review · 2025Article
- Diverging spatiotemporal trajectories of thyroid cancer incidence and mortality in reproductive-age women: a socio-demographic index stratified analysis of GBD 2021 data.Gland surgery · 2025Article
- Epidemiology of thyroid cancer in Asia in 2020 and its projection to 2040.BMC public health · 2025Article
- Smarter biopsy decisions in thyroid nodules via dual-modal photoacoustic and ultrasound imaging.Science advances · 2025Article
- Global, regional, and national trends in thyroid cancer burden (1990-2021): Insights from the GBD 2021 study.Biomolecules & biomedicine · 2025Article
- Continued rise in the incidence of thyroid cancer in Iran: true increase or overdiagnosis?Journal of diabetes and metabolic disorders · 2025Article
- Prediction of BRAF and TERT status in PTCs by machine learning-based ultrasound radiomics methods: A multicenter study.Journal of clinical & translational endocrinology · 2025Article
- Dual roles of long non-coding RNAs in thyroid cancer: regulation of programmed cell death pathways.Medical oncology (Northwood, London, England) · 2025Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo investigate the burden of thyroid cancer and its attributable risk factors in 204 countries and territories during 30 years.
methodsWe extracted data from the Global Burden of Disease (GBD) 2019 database, including incidence, mortality, disability-adjusted life-years (DALYs), and the attributable risk factors of thyroid cancer from 1990 to 2019. Estimated annual percentage changes (EAPC) were calculated to assess the changes in age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALYs rate (ASDR). We also examined the associations between cancer burden and the sociodemographic index (SDI).
resultsThe global new cases, death, and DALYs of thyroid cancer in 2019 were 233 847 (95% UI: 211 637-252 807), 45 576 (95% UI: 41 290-48 775), and 1 231 841 (95% UI: 1 113 585-1 327 064), respectively. From 1990 to 2019, the ASIR of thyroid cancer showed an upward trend (EAPC = 1.25), but ASMR (EAPC = -0.15) and ASDR (EAPC = -0.14) decreased. The burden of thyroid cancer varied at regional and national levels, but the association between ASIR and SDI was positive. We found that the burden of thyroid cancer was mainly concentrated in females and that the age of onset tended to be younger. The proportion of DALYs from thyroid cancer attributable to high body-mass index was higher in high SDI regions, especially in males.
conclusionsThe global incidence of thyroid cancer has continued to increase in the past three decades. The high body-mass index as an important risk factor for thyroid cancer deserves greater attention, especially in high SDI regions.
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