Evidence map›Paper›PMID 34355307›Full record

ArticleEating and weight disorders : EWD2022

Behavioral circadian phenotypes are associated with the risk of elevated body mass index.

Muhammad Alsayid, Mohammed Omer Khan, Darbaz Adnan, Heather E Rasmussen, Ali Keshavarzian, Faraz Bishehsari

Open access · greenAbstract read
In one paragraph

Article in Eating and weight disorders : EWD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Muhammad Alsayid *Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA.
Mohammed Omer Khan *Department of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA.
Darbaz AdnanDepartment of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA.
Heather E RasmussenDepartment of Nutrition and Dietetics, University of Nebraska-Lincoln, Lincoln, NE, USA.
Ali KeshavarzianDepartment of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA.
Faraz BishehsariDepartment of Internal Medicine, Division of Digestive Diseases and Nutrition, Rush University Medical Center, Chicago, IL, USA. Faraz_Bishehsari@rush.edu.ORCID http://orcid.org/0000-0001-5644-2586
Rush University Medical Center · USUniversity of Nebraska–Lincoln · US

Funding

J. NRSA Training CoreTL1TR002388 · NCATS · UNIVERSITY OF CHICAGO · PI ALI KESHAVARZIAN, Sonia Kupfer · 2017 to 2026
$6.7M
Abnormal Food Timing and Circadian Dyssynchrony in Alcohol Induced Colon CarcinogenesisK23AA025387 · NIAAA · RUSH UNIVERSITY MEDICAL CENTER · PI BISHEHSARI, FARAZ · 2018 to 2022
$945k
NCATS NIH HHS TL1 TR002388NCATS NIH HHS TL1TR002388NIAAA NIH HHS K23 AA025387NIH HHS AA025387
6 · The paper itself

Abstract

backgroundMetabolic dysfunction and obesity rates are on the rise. Although the central modes of circadian disruption has been studied in relation to the risk of obesity, the role of eating time has remained unclear. Here, we aimed to assess circadian behavioral phenotypes and their association with the risk of elevated body mass index (BMI).

methodsThis was a prospective cross-sectional study of individuals presenting for colorectal cancer screening colonoscopy. Participants completed demographic questionnaires, The Munich ChronoType Questionnaire (MCTQ), and Food Timing Screener (FTS). The primary outcome of the study was the association between circadian phenotypes and elevated BMI.

resultsA total of 488 individuals completed the survey, with a mean (SD) age of 57.5 (10.8) years. The mean body mass index (BMI) was 28.8 (6.1) kg/m

conclusionThe combination of late chronotype and irregular food timing, representative of a behavioral circadian rhythm disruption, is associated with higher rates of elevated BMI. The majority of individuals with this abnormal circadian phenotype were younger than 60 years old. This observation is especially relevant because of the ongoing rise in the obesity rates among young adults. LEVEL III: Evidence obtained from well-designed cohort or case-control analytic studies.

Indexed as

Circadian RhythmSleepBody Mass IndexCross-Sectional StudiesHumansObesityPhenotypeProspective StudiesSurveys and QuestionnairesBody mass indexChronotypeCircadian phenotypeFood timingMetabolic dysfunctionObesityOverweight

Identifiers

PMID34355307
PMCPMC8816962
OpenAlexW3188632477

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.