Evidence map›Paper›PMID 34355264›Full record

ReviewPediatric radiology2022

The radiologist's role in assessing differences of sex development.

Anastasia L Hryhorczuk, Andrew S Phelps, Richard N Yu, Jeanne S Chow

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Differences of sex development.Nature reviews. Disease primers · 2025
    Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anastasia L HryhorczukSection of Pediatric Radiology, C. S. Mott Children's Hospital, Department of Radiology, Michigan Medicine, 1500 E. Medical Center Drive, Ann Arbor, MI, 48109-4252, USA. ahryhorc@med.umich.edu.ORCID http://orcid.org/0000-0003-1817-6904
Andrew S PhelpsDepartment of Radiology, Oregon Health & Science University, Portland, OR, USA.
Richard N YuDepartment of Urology, Boston Children's Hospital, Boston, MA, USA.
Jeanne S ChowDepartment of Radiology, Boston Children's Hospital, Boston, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When infants are identified with a difference of sex development (DSD), a thoughtful approach to imaging is essential to appropriate clinical management. This review provides a comprehensive guide for radiologists who are tasked with performing this critical assignment. We review the embryologic basis of DSDs, with attention to the imaging findings that can indicate specific diagnoses. We also discuss techniques for optimal imaging, including strategies for identifying the gonads by US, tactics for performing genitograms with fluoroscopy and contrast-enhanced US, and the appropriate utilization of MRI. Finally, we review the clinical data and imaging findings that characterize some of the most common DSDs, including congenital adrenal hyperplasia, complete androgen insensitivity syndrome and gonadal dysgenesis.

Indexed as

Adrenal Hyperplasia, CongenitalDisorders of Sex DevelopmentTurner SyndromeFemaleHumansInfantMaleRadiologistsSexual DevelopmentAmbiguous genitaliaChildrenComplete androgen insensitivity syndromeCongenital adrenal hyperplasiaDifference of sex developmentDisorder of sexual differentiationGenitogramGonadal dysgenesisInfantMagnetic resonance imagingNeonateUltrasound

Identifiers

PMID34355264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.