Evidence map›Paper›PMID 34355185›Full record

ArticleRSC medicinal chemistry2021

Synthesis and pharmacological evaluation of [

Filomena Mattner, Andrew Katsifis, Thomas Bourdier, Christian Loc'h, Paula Berghofer, Christopher Fookes, Tzong-Tyng Hung, Timothy Jackson, David Henderson, Tien Pham and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. TSPO Radioligands for Neuroinflammation: An Overview.Molecules (Basel, Switzerland) · 2024
    Review
  3. Review
  4. Pharmaceutics · 2022
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 4 countries.

Filomena MattnerDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0002-5528-5328
Andrew KatsifisDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0002-0856-9985
Thomas BourdierDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0003-0640-9985
Christian Loc'hAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0003-4873-7813
Paula BerghoferAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0003-3374-4113
Christopher FookesAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-9301-5994
Tzong-Tyng HungBiological Resources Imaging Laboratory, University of New South Wales Sydney NSW Australia.ORCID https://orcid.org/0000-0002-2904-2664
Timothy JacksonAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-7869-5768
David HendersonDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0001-5114-1223
Tien PhamAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-6942-3699
Brendan J LeeBiological Resources Imaging Laboratory, University of New South Wales Sydney NSW Australia.ORCID https://orcid.org/0000-0002-0347-2105
Rachael ShepherdAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-9403-9859
Ivan GreguricAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-2291-9881
Naomi WyattAustralian Nuclear Science and Technology Organisation Lucas Heights NSW Australia.ORCID https://orcid.org/0000-0002-5311-1623
Thanh LeDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0001-8172-3945
Jackson PoonDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0001-7595-0455
Carl PowerBiological Resources Imaging Laboratory, University of New South Wales Sydney NSW Australia.ORCID https://orcid.org/0000-0003-2357-2987
Michael FulhamDepartment of Molecular Imaging, Royal Prince Alfred Hospital Camperdown NSW 2050 Australia andrewk@nucmed.rpa.cs.nsw.gov.au.ORCID https://orcid.org/0000-0003-0602-6319
Australian Nuclear Science and Technology Organisation · AURoyal Prince Alfred Hospital · AUUNSW Sydney · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiopharmaceuticals that target the translocator protein 18 kDa (TSPO) have been investigated with positron emission tomography (PET) to study neuroinflammation, neurodegeneration and cancer. We have developed the novel, achiral, 2-phenylimidazo[1,2-

Identifiers

PMID34355185
PMCPMC8292990
OpenAlexW3153055076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.