Evidence map›Paper›PMID 34355156›Full record

ArticleSurgery open science2021

Predictive factors of perforated appendicitis: Impact of the C-reactive protein level.

Shiori Yamazaki, Yusuke Shimodaira, Akira Kobayashi, Manabu Takata, Kaori Hayashibara, Masahiro Sakon, Yasushi Sekino, Masao Okada, Yusuke Takahashi, Masatoshi Shimura and 2 more

Open access · goldAbstract read
In one paragraph

Article in Surgery open science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Shiori YamazakiNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Yusuke ShimodairaNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Akira KobayashiNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Manabu TakataNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Kaori HayashibaraNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Masahiro SakonNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Yasushi SekinoNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Masao OkadaNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Yusuke TakahashiNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Masatoshi ShimuraNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Hitoshi SekiNagano Municipal Hospital, Department of Digestive Surgery, Nagano, Japan.
Yuji SoejimaDivision of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.
Nagano Municipal Hospital · JPShinshu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerforated appendicitis without an associated abscess necessitates emergency surgery. However, it is difficult to predict the presence of perforation before surgery, and the predictive factors are still unclarified. Our purposes were to characterize a patient population with perforated appendicitis without an associated abscess to identify the preoperative predictive factors of appendiceal perforation.

methodsWe retrospectively identified 150 patients who underwent appendectomy for acute appendicitis at our institution from June 2018 to November 2020. Logistic regression analysis was performed to analyze the concurrent effects of various factors on the prevalence of perforated appendicitis.

resultsForty (29%) of 150 patients had appendiceal perforation detected intraoperatively. Of these 40 patients, only 19 had appendiceal perforation detected on preoperative computed tomography. Multivariable analysis found that a higher C-reactive protein level, higher total bilirubin level, and the presence of an appendiceal fecalith were independent predictive factors for appendicitis with perforation.

conclusionOur analysis suggests that the presence of an appendiceal fecalith, a total bilirubin level of more than 21.38 μmol/L, and a C-reactive protein level of more than 3.0 × 10

Indexed as

appendicitisConstructed wetland (CW)C-reactive proteinperforation

Identifiers

PMID34355156
PMCPMC8319788
OpenAlexW3173492171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.