Evidence map›Paper›PMID 34354985›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Adhesive Tissue Engineered Scaffolds: Mechanisms and Applications.

Shuai Chen, Carmen J Gil, Liqun Ning, Linqi Jin, Lilanni Perez, Gabriella Kabboul, Martin L Tomov, Vahid Serpooshan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. 2D MoSNano convergence · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Physicochemical Principles of Adhesion Mechanisms in the Brain.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shuai ChenDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Carmen J GilDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Liqun NingDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Linqi JinDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Lilanni PerezDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Gabriella KabboulDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Martin L TomovDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.
Vahid SerpooshanDepartment of Biomedical Engineering, Emory University School of Medicine, Georgia Institute of Technology, Atlanta, GA, United States.

Funding

Leveraging 3D bioprinted organoid constructs to pattern and model human brain developmentR01MH126195 · NIMH · EMORY UNIVERSITY · PI SERPOOSHAN, VAHID, SLOAN, STEVEN A · 2021 to 2025
$3.3M
Molecular and Cellular Mechanisms of Neonatal Cardiac Development and RepairR00HL127295 · NHLBI · EMORY UNIVERSITY · PI SERPOOSHAN, VAHID · 2018 to 2020
$729k
NHLBI NIH HHS R00 HL127295NIMH NIH HHS R01 MH126195
6 · The paper itself

Abstract

A variety of suture and bioglue techniques are conventionally used to secure engineered scaffold systems onto the target tissues. These techniques, however, confront several obstacles including secondary damages, cytotoxicity, insufficient adhesion strength, improper degradation rate, and possible allergic reactions. Adhesive tissue engineering scaffolds (ATESs) can circumvent these limitations by introducing their intrinsic tissue adhesion ability. This article highlights the significance of ATESs, reviews their key characteristics and requirements, and explores various mechanisms of action to secure the scaffold onto the tissue. We discuss the current applications of advanced ATES products in various fields of tissue engineering, together with some of the key challenges for each specific field. Strategies for qualitative and quantitative assessment of adhesive properties of scaffolds are presented. Furthermore, we highlight the future prospective in the development of advanced ATES systems for regenerative medicine therapies.

Indexed as

adhesive tissue engineering scaffoldbone regenerationcardiac regenerationcartilage regenerationnerve regenerationscaffoldtissue regenerationwound repair

Identifiers

PMID34354985
PMCPMC8329531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.