Evidence map›Paper›PMID 34354970›Full record

ReviewFrontiers in pediatrics2021

Ikaros-Associated Diseases: From Mice to Humans and Back Again.

Brigette Boast, Cristiane de Jesus Nunes-Santos, Hye Sun Kuehn, Sergio D Rosenzweig

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. The Impact of Zinc on T Cell Motility and the Immunological Synapse.International journal of molecular sciences · 2026
    Article
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  3. Review
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  10. Impaired tissue homing by the Ikzf3Frontiers in immunology · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Brigette BoastDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.
Cristiane de Jesus Nunes-SantosImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Hye Sun KuehnImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, United States.
Sergio D RosenzweigImmunology Service, Department of Laboratory Medicine, National Institutes of Health Clinical Center, Bethesda, MD, United States.
National Institutes of Health Clinical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The normal expression of Ikaros (IKZF1) is important for the proper functioning of both the human and murine immune systems. Whilst our understanding of IKZF1 in the immune system has been greatly enhanced by the study of mice carrying mutations in

Indexed as

B cellcytopeniahypogammaglobulinemiainborn errors of immunityinfectionprimary immunodeficiencyT celltranscription factors

Identifiers

PMID34354970
PMCPMC8330404
OpenAlexW3184380370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.